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There are 278 twenty-one-letter words containing A, D, E, F and R

abdominocardiac␣reflexabsent-minded␣professoradditive␣manufacturingadmiral␣of␣the␣Swiss␣Navyafraid␣of␣one's␣own␣shadowafter␣all␣is␣said␣and␣donealgebraic␣number␣fieldsall␣is␣fair␣in␣love␣and␣warall␣the␣world␣and␣his␣wifeanterior␣median␣fissureanticonfederationistsArlecdon␣and␣Frizingtonarmored␣combat␣fightingarteries␣of␣Adamkiewiczartificially␣sweetenedas␣far␣as␣the␣eye␣could␣seeBasset␣Fauve␣de␣Bretagnebastard␣big-footed␣mousebatted␣for␣the␣other␣sidebatted␣for␣the␣other␣teamBellman-Ford␣algorithmsblack-billed␣flycatcherblack-tailed␣flycatcherblue-breasted␣fairywrenbromotetrahydrofuransbuffalobur␣nightshadesbuffaloburr␣nightshadebuff-breasted␣sandpiperbuy␣a␣dog␣and␣bark␣oneselfcalibrated␣focal␣lengthCalifornia␣Spangled␣Catcall␣the␣fire␣departmentcast␣one's␣net␣far␣and␣widecertificates␣of␣depositchannel␣of␣distributionChiari-Frommel␣syndromechlorine␣pentafluoridechlorodifluoromethanechlorotetrahydrofuranchondroitinsulfatasesCity␣and␣County␣of␣Denverclosed␣feedwater␣heaterCode␣of␣Military␣Justicecommand-line␣interfaces command␣line␣interfacescomplex-differentiableconfidential␣informantcongenital␣heart␣defectcooperative␣federalismcorridor␣of␣uncertaintycottage␣food␣operationscourt␣of␣second␣instancecurse␣of␣dimensionalitycytidylyltransferasesdance␣to␣a␣different␣tunedark␣as␣the␣inside␣of␣a␣cowdark␣green␣fritillariesdeacetylmarsformosidedeepwater␣cardinalfishdeflavorizing␣machinesdeformation-retracting deformation␣retractingdenial-of-service␣attackdeprofessionalizationdichlorofluoromethanedictionary␣definitionsdifferential␣diagnosesdifferential␣diagnosisdifferential␣equationsdifferential␣operatorsdifferential␣structuredig␣one's␣grave␣with␣a␣forkdihydroergocalciferoldiphosphotransferasesdirector␣of␣photographydisjunctive␣normal␣formDoctor␣of␣Humane␣Lettersdoctrine␣of␣equivalentsdonor-specific␣antibodydrunk␣as␣a␣fiddler's␣bitchDuke␣of␣Exeter's␣daughterdumber␣than␣a␣box␣of␣rocksduress␣of␣circumstancesdwarf␣spheroidal␣galaxyEast␣African␣FederationEast␣Riding␣of␣Yorkshireelectromagnetic␣fieldsenantiodifferentiatedenumerative␣definitionerr␣on␣the␣side␣of␣cautionfactory␣method␣patternsfair-weather␣friendshipFalklands␣fritillariesfallen␣asleep␣in␣the␣Lordfallen␣at␣the␣last␣hurdleFallen␣Jerusalem␣Islandfall␣into␣the␣wrong␣handsfalls␣at␣the␣final␣hurdlefalse␣saber-toothed␣catsfalse␣sabre-toothed␣catsfeed␣a␣cold,␣starve␣a␣feverfee␣simple␣determinablefetal␣alcohol␣syndromesfind␣the␣latchstring␣outfine-needle␣aspirationsfingers␣and␣toes␣crossed

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