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There are 677 sixteen-letter words containing A, E, M, N, S and Y

(page 5)

tetramethysilanethanatochemistrythermodynamicisttocodynamometerstranscarbamylasetransfer␣paymentstransformativelytransmethylationtransplantectomytranstemporalitytreeman␣syndromestridimensionallytrimethoxysilanetrimethylalkanestrimethylstannyltrypanosomacidestrypanosomicidestwo-dimensionallytympanic␣cavitiestympanosclerosistympanosclerotictympanostapedialunemployablenessunidimensionallyunimpressionablyunmistakeabilityunsentimentalityunsystematicallyunsystematic␣riskunsystematizablevanadomolybdatesvideourodynamicsvoluntary␣muscleswears␣too␣many␣hatsWestminster␣AbbeyWilliams␣syndromeYankee␣tunesmithsyellow␣journalismYoneda␣embeddings

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 720 words
  • Spanish Wiktionary: 11 words
  • Italian Wiktionary: no word
  • German Wiktionary: 133 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 66 words

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