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There are 766 eighteen-letter words containing A, I, O, P, S and Y

(page 4)

pharyngointestinalpharyngolaryngitespharyngolaryngitispharyngotonsilitisphenylboronic␣acidsphenylchlorosilanephosphatidylserinephosphoacetylationphosphoribosylatedphosphorocyanidatephosphorylceramidephosphorylcreatinephotophysiologicalphotoswitchabilityphotosyntheticallyphylobetadiversityphylostratigraphicphylotranscriptomephysical␣geographerphysicochemicalismphysicomathematicsphysicotheologicalphysiogeographicalphysiopathogenesisphysiopathologicalphysiopathologistsphytophysiologicalphytoplanktivorousphytostabilisationphytostabilizationpin␣a␣rose␣on␣your␣nosepiss␣money␣up␣the␣wallPittsylvania␣Countyplastohydroquinoneplaying␣Nostradamusplay␣one's␣cards␣rightplays␣one's␣hand␣rightplay␣well␣with␣othersplay␣with␣edged␣toolsplay␣with␣house␣moneyplethysmographicalpoikiloblasticallyPoland␣Is␣Not␣Yet␣Lostpolicy␣interest␣ratepolyacrylonitrilespolybenzimidazolespolychemotherapiespolychromatophilespolyesterificationpolyfunctionalisedpolygamma␣functionspolygamomonoeciouspolyhydric␣alcoholspolymerizabilitiespolymolecularitiesPolynesian␣Trianglepolypharmacologiespolyphenoloxidasespolyphenylalanines poly-phenylalaninespolyphosphoric␣acidpolysomnographicalpolysomnographistspolysporangiophytepolyvictimizationspolyvinylsiloxanespopular␣etymologiespopulation␣pyramidsportal␣hypertensionpositional␣asphyxiapositive␣neutralitypostconceptionallypostdepositionallypostdiagnosticallypostfoundationallypostlinguisticallypostpericardiotomypostpolymerizationpostpsychoanalyticpostranslationallypotassium␣guanylatepotassium␣hydroxidepotentiostaticallypour␣honey␣in␣one's␣earprecompositionallyprecrystallizationpredispositionallyprephosphorylatingprephosphorylationpresuppositionallypresymptomaticallypresynchronizationprimary␣legislationprobability␣densityprobability␣measureproofs␣by␣exhaustionpropagandisticallypropionylpromasineproposition␣playersproprietary␣eponymsprosopographicallyproteoaminoglycansprotocycloceratidsprotodesilylationsprotomyofibroblastprotoplanetary␣discprotoplanetary␣diskprotopsychologicalpseudoanaphylacticpseudobiologicallypseudoetymologicalpseudogynecomastiapseudoheritabilitypseudohyperkalemiapseudohyponatremiapseudometaphysicalpseudomythologicalpseudoparaphylliumpseudopolycythemiapseudopsychopathicpseudosynaesthesiapseudouridylationspsychic␣photographypsychoacousticallypsychoacousticianspsychoanalyticallypsychobiographicalpsychobiologicallypsychocivilizationpsychocosmologicalpsychodermatologicpsychodramaticallypsychogeographicalpsychogeriatricianpsychographologistpsychohistoricallypsycholinguisticalpsychological␣slipspsychologisticallypsychomanipulationpsychomanipulativepsychoneurologicalpsychoneuroticallypsychopathologicalpsychopathologistspsychopathologizedpsychopathologizespsychopharmaceuticpsychophonetically

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 749 words
  • Spanish Wiktionary: 3 words
  • Italian Wiktionary: no word
  • German Wiktionary: 39 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 26 words

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