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There are 58 twenty-one-letter words containing A, 2D, E, F and R

abdominocardiac␣reflexabsent-minded␣professoradditive␣manufacturingafraid␣of␣one's␣own␣shadowafter␣all␣is␣said␣and␣doneall␣the␣world␣and␣his␣wifeArlecdon␣and␣Frizingtonbastard␣big-footed␣mousebatted␣for␣the␣other␣sidebuff-breasted␣sandpiperbuy␣a␣dog␣and␣bark␣oneselfcast␣one's␣net␣far␣and␣wideCity␣and␣County␣of␣Denverclosed␣feedwater␣heaterdance␣to␣a␣different␣tunedark␣as␣the␣inside␣of␣a␣cowdeacetylmarsformosidedeepwater␣cardinalfishdictionary␣definitionsdifferential␣diagnosesdifferential␣diagnosisdihydroergocalciferoldonor-specific␣antibodydrunk␣as␣a␣fiddler's␣bitchDuke␣of␣Exeter's␣daughterdwarf␣spheroidal␣galaxyenantiodifferentiatedfeed␣a␣cold,␣starve␣a␣feverfingers␣and␣toes␣crossedforewarned␣is␣forearmedfork-tailed␣bush␣katydidgo␣the␣way␣of␣the␣dodo␣birdGrand␣Lodge␣Freemasonryhairy-eared␣dwarf␣lemursHeads␣of␣the␣Valleys␣RoadHighcliffe␣and␣Walkfordlooked␣before␣one␣leapedmarch␣to␣a␣different␣drummatters␣of␣life␣and␣deathnature-deficit␣disorder nature␣deficit␣disorderolive-sided␣flycatchersone␣card␣shy␣of␣a␣full␣deckorange-spotted␣drone␣flyPicard-Lindef␣theoremradio␣direction␣findersred-breasted␣flycatcherself-deserting␣avoidantsilane-modified␣polymersoftware␣defined␣radiosstand␣on␣the␣shoulders␣ofsurface-supplied␣divingtrans-identified␣femaleunsaturated␣fatty␣acidsurea-formaldehyde␣resinwomen␣and␣children␣firstWoodward-Hoffmann␣rulesYarnfield␣and␣Cold␣Meece

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