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There are 281 twenty-one-letter words containing A, E, F, 2R and S

absent-minded␣professoraccessary␣after␣the␣factaccessory␣after␣the␣factaffine␣transformationsaffirmative␣resolutionAfrican␣forest␣elephanta␣fry␣short␣of␣a␣Happy␣Mealairbreathing␣catfishesair␣traffic␣controllersalgebraic␣number␣fieldsall␣is␣fair␣in␣love␣and␣waraminoacyltransferasesangular␣unconformitiesanimal␣control␣officersAnkole␣African␣mole-ratsanswer␣the␣call␣of␣natureanterior␣median␣fissurearabinosyltransferasearguments␣from␣illusionarteries␣of␣Adamkiewiczarteriovenous␣fistulasartificial␣respirationarylsulfotransferasesarylsulphotransferaseAsian␣brown␣flycatchersas␣if␣there␣is␣no␣tomorrowatmospheric␣refractionatomic␣force␣microscopeatomic␣force␣microscopyautonomous␣prefecturesbatted␣for␣the␣other␣sideBellman-Ford␣algorithmsblueberry␣muffin␣babiesblue-breasted␣fairywrenbox␣oneself␣into␣a␣cornerbromotetrahydrofuransbuffaloburr␣nightshadebuff-breasted␣sandpipercafeteria␣ChristianityCalifornia␣pepper␣treescarbamoyltransferasescast␣pearls␣before␣swinecasualty␣of␣superiorityChiari-Frommel␣syndromeclosed␣feedwater␣heatercollaborative␣softwarecooperative␣federalismcountertransferentialcountries␣of␣provenancecourts␣of␣first␣instancecritical␣success␣factorcytidylyltransferasesdark␣green␣fritillariesdeacetylmarsformosidedeepwater␣cardinalfishdifferential␣operatorsdifferential␣structuredig␣one's␣grave␣with␣a␣forkdiphosphotransferasesdisjunctive␣normal␣formDoctor␣of␣Humane␣Lettersdrunk␣as␣a␣fiddler's␣bitchDuke␣of␣Exeter's␣daughterdumber␣than␣a␣box␣of␣rocksduress␣of␣circumstancesdwarf␣spheroidal␣galaxyEast␣African␣FederationEast␣Riding␣of␣YorkshireEinstein␣refrigeratorselectrotransformationembarrassment␣of␣richesenvironmental␣refugeeserr␣on␣the␣side␣of␣cautionfactory␣method␣patternsfair-weather␣friendshipFalklands␣fritillariesfamilies␣of␣procreationfarnesylpyrophosphatefast␣Fourier␣transformsfeed␣a␣cold,␣starve␣a␣feverferroelectric␣crystalsFile␣Transfer␣Protocolsfine-structure␣constant fine␣structure␣constantfingers␣and␣toes␣crossedfingers␣in␣the␣cookie␣jarfirm␣hands␣at␣the␣tillersfirm␣hands␣on␣the␣tillersfirst␣angle␣projectionsfirst␣olive␣out␣of␣the␣jarFleming's␣right-hand␣rulefluorodesulfurizationfluorotriphenylsilanefor␣all␣intense␣purposesforeign␣accent␣syndromeforewarned␣is␣forearmedformiminotransferasesfortune␣favors␣the␣bravefortune␣favours␣the␣boldfragmentation␣grenadesFrankenstein's␣monstersFrench␣and␣Iroquois␣Warsfreshwater␣pearl␣musselFriedel-Crafts␣reactionfructoligosaccharidesfructooligosaccharidefructosyltransferasesgalactosyltransferasegather␣oneself␣together

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