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There are 42 sixteen-letter words containing 2A, 2E, 2F and O

affaires␣d'honneuraffected␣equationaffectionatenessaffiliate␣networkafternoon␣farmersareas␣of␣influencebreath␣of␣fresh␣aircaffeoylquinatescannonball␣effectcreatinolfosfatedeafferentationsdecaffeinizationdysafferentationeffectualizationfallen␣on␣deaf␣earsfallen␣on␣one's␣facefederal␣officialsfore-and-aft-riggedfundamental␣forcegreat␣balls␣of␣firehabitual␣offenderhead␣off␣at␣the␣passlaugh␣one's␣head␣offMarangoni␣effectsmatter-of-factnessnondecaffeinatedoffer␣affordancesoffice␣landscapesoff␣the␣beaten␣pathovercaffeinatingOvsiankina␣effectpass␣oneself␣off␣asreafforestationsscare␣the␣pants␣offself-flagellationself-flagellatorysnuff␣box␣sea␣beanssulfotransferasesurface-to-surfacetake␣one's␣hat␣off␣totraffic␣generatorunaffectionately

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