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There are 27 sixteen-letter words containing 2A, 2N, 2P and U

alpha-beta␣pruningappendiculariansappropinquationsclean␣up␣one's␣platecounterappellantGalapagos␣penguin Galápagos␣penguininfrapopulationsJapanese␣pumpkinsmany␣happy␣returnsneuropathic␣painsPapua␣New␣GuineansplanktonophagouspostmanipulationpreantepenultimaProto-Pama-Nyunganpseudo-penannularpunctuation␣spaceputting␣a␣damper␣onsplanchnopleuraltranspopulationsunappeasablenessunderapplicationunderpreparationundisappointableunpropagandisticupland␣sandpipers

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 52 words
  • Spanish Wiktionary: 2 words
  • Italian Wiktionary: 7 words
  • German Wiktionary: 19 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 7 words

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