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There are 169 sixteen-letter words containing A, 2E, 2M and 2S

academic␣costumesaccommodablenessaccommodatednessamusement␣arcadesaneurysmectomiesanteromesoscutumantisymmetrisersantisymmetrizersassumed␣the␣mantleassumes␣the␣mantleasymmetricalnessasymmetric␣metersbeat␣someone's␣timeblue␣swimmer␣crabscallosumectomiescementoblastomaschamber␣ensembleschameleon␣schemaschemosystematicschromomethylasescommensuratenesscommissioneratescommunicablenesscomplementalnesscomplete␣measuresconsummativenesscorneodesmosomalcrash␣test␣dummiescross␣peen␣hammersdecommissionabledefense␣mechanismdesert␣rheumatismdisembarrassmentdissepimentariumDomain␣Name␣Systemdrives␣someone␣madectocommensalismemblematicalnessemblematologistsendocommensalismessential␣infimumestablishmentismexperimentalismsgammaherpesvirusGeneva␣mechanismsgenome␣assembliesgiant␣mouse␣lemurshaemochromatoses hæmochromatoseshammerhead␣sharkshemiascomycetoushow␣embarrassmenthypermagnesemiashypermetabolismsimmeasurablenessimmensurablenessimmersion␣heatersimmethodicalnessimmunoaccessibleimmunodepressantimmunoresistanceimpact␣statementsimpossible␣dreamsincome␣statementsincommensurablesin␣no␣small␣measureJames's␣flamingoeslateral␣meristemslines␣of␣scrimmagemacromelanosomesmacrostemonosidemade␣an␣impressionmade␣matters␣worseMagdalene␣asylumsmagnesium␣sulfatemagnesium␣sulfidemake␣an␣impressionmake␣matters␣worsemakes␣common␣causemammarenavirusesmanagement␣systemman-to-man␣defensesmasked␣palm␣civetsmass␣spectrometermass␣spectrometrymaster␣of␣one's␣timemathematicastersmealymouthednessmeasurement␣goodsmechanosensillummecysmaucheniidsmediastinotomiesmelanophagosomesmelastomataceousmemorial␣servicesMendlesham␣chairsmermaid's␣toenailsMesoamericanistsmessengers-at-armsmessiah␣complexesmetal␣homeostasismetastable␣isomermetastasectomiesmetastatectomiesmetempsychosicalmethylhistaminesmethylmannosidesmicromelanosomesMiddle␣Easternismmidsummer␣daisiesmidsummer␣madnessmines␣and␣mineralsmisappraisementsmisascertainmentmissense␣mutationmission␣statementmisunderestimatemomentaneousnessMorris␣water␣mazesmoules␣marinièresmulti-agent␣systemmyelocytomatosesnonemphysematousOmmaya␣reservoirson␣first-name␣termsovermeasurementsPenrose␣mechanismpercussion␣hammerphaeomelanosomespostmeasurementsPseudomacedonismpseudomembranouspygmy␣sperm␣whalesquasimesenchymalradial␣symmetriesread␣someone's␣mindreal␣number␣systemroeslerstammiidssame-sex␣marriagesSchumpeterianismscreaming␣meemiesseismometrographselenometabolismsemidomesticated semi-domesticatedsemimanufacturesSherman␣statementsilvery␣marmosetssimple␣majoritiessmall␣firm␣effectsspamvertizementsstage␣micrometerssteam␣locomotivesstone␣man␣syndromesubmembranaceoussummer␣snowflakessun␣anemone␣shrimp

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