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There are 26 sixteen-letter words containing A, 2E, 2M and 2U

anteromesoscutumArmenian␣cucumberexecutive␣summarygiant␣mouse␣lemursheavy␣metal␣umlautimmunoneutraliseimmunoneutralizeimmunoregulativejuxtamembraneousmagnesium␣sulfatemagnesium␣sulfidemake␣up␣the␣numbersmultitemperatureMurrumbidgee␣jamspseudomembranousruptured␣membranescream␣blue␣murdersemimanufacturessevum␣benzoinatumsubmembranaceoussupercommutativeterminus␣ante␣quemulceromembranousundermeasurementunexcommunicatedunion␣wage␣premium

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