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There are 329 twenty-one-letter words containing A, D, E, 2I and 2S

abdominohysterotomiesacetylglucosaminidaseacetylhexosaminidasesadaptive␣immune␣systemsadenosinetriphosphate adenosine␣triphosphateadenotonsillectomizesadministrative␣regionsadmiral␣of␣the␣Swiss␣Navyadrenocorticosteroidsafter␣all␣is␣said␣and␣doneagricultural␣densitiesAldabra␣giant␣tortoisesalgorithmic␣randomnessanterior␣median␣fissureanticonfederationistsantideconstructionistantitranscendentalismAnton-Babinski␣syndromearctic␣ground␣squirrelsArndt-Eistert␣synthesisAsk␣a␣Stupid␣Question␣Dayattends␣to␣one's␣knittingauctorial␣descriptivesbackwards␣time␣machinesbad␣things␣come␣in␣threesBangka␣Belitung␣Islandsbarking␣dogs␣seldom␣bitebiting␣someone's␣head␣offblack-striped␣wallabiesblew␣this␣popsicle␣standblow␣this␣popsicle␣stand blow␣this␣Popsicle␣standBritish␣Virgin␣Islanderbuilds␣castles␣in␣the␣airbulletin␣board␣servicescarboxamidoadenosinescardiovascular␣diseasecellooligosaccharidescertificates␣of␣depositChatham␣Islands␣penguinchemoradiosensitiserschemoradiosensitivitychi-square␣distributionchitooligosaccharideschondroitinsulfataseschondroitinsulphatasechronic␣wasting␣diseaseCocos␣(Keeling)␣Islanderscognitive␣disabilitiescold␣agglutinin␣diseasecombination␣sandwichescombined␣braking␣systemcommand␣responsibilitycomprador␣bourgeoisiescondensation␣reactionsconfessional␣debuggingconstructive␣dischargeconstructive␣dismissalcontradictionlessnesscontradictions␣in␣termscontradistinctivenesscrystal␣radio␣receiverscuriouser␣and␣curiousercurse␣of␣dimensionalitycystofilobasidiaceousdark␣as␣the␣inside␣of␣a␣cowdark␣crimson␣underwingsdatabase␣administratordata␣processing␣machinedeconfessionalisationdeconfessionalizationdefect␣of␣one's␣qualitiesdegrammaticalisationsDejerine-Sottas␣diseasedelusional␣parasitosisdemand␣characteristicsdemonstrative␣legaciesdenotational␣semanticsdeprofessionalizationderesponsibilisationsderesponsibilizationsderivative␣instrumentsdesacetylscillirosidedescriptive␣adjectivesdescriptive␣statisticsdevil␣lies␣in␣the␣detailsdick-measuring␣contestsdielectric␣absorptionsdifferential␣diagnosesdifferential␣diagnosisdigital␣pre-distortionsdigital␣subscriber␣linedimensionless␣quantitydimethylpolysiloxanesdips␣one's␣toe␣in␣the␣waterdisappearing␣carriagesdisappears␣into␣thin␣airdiscretionary␣accountsdiscretionary␣spendingdiscriminative␣stimulidisestablishmentariandishonorable␣dischargedisproportionablenessdisseminated␣sclerosisdissociation␣reactionsdissociative␣disordersdistributed␣hash␣tablesdo␣a␣land-office␣businessdo␣bears␣shit␣in␣the␣woodsdolichyldiphosphatasedonationes␣mortis␣causadrive␣one's␣pigs␣to␣marketdrives␣the␣porcelain␣bus

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