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There are 66 twenty-one-letter words containing A, D, F, 2O and 2S

absent-minded␣professorafraid␣of␣one's␣own␣shadowanticonfederationistsbastard␣big-footed␣mousebiting␣someone's␣head␣offbitten␣someone's␣head␣offcertificates␣of␣depositchondroitinsulfatasesconfessional␣debuggingcourt␣of␣second␣instancecurse␣of␣dimensionalitycystofilobasidiaceousdark␣as␣the␣inside␣of␣a␣cowdeacetylmarsformosidedeconfessionalisationdeconfessionalizationdefect␣of␣one's␣qualitiesdeprofessionalizationdesulfoglucosinolatesdiphosphotransferasesdo␣a␣land-office␣businessEast␣Riding␣of␣Yorkshirefalse␣saber-toothed␣catsfalse␣sabre-toothed␣catsfetal␣alcohol␣syndromesfingers␣and␣toes␣crossedFirst␣New␣England␣Schoolfought␣like␣cats␣and␣dogsFrench␣and␣Iroquois␣Warsfructoligosaccharidesget␣one's␣affairs␣in␣ordergrandmother's␣footstepshaberdasher␣of␣pronounsHeads␣of␣the␣Valleys␣Roadhistodifferentiationshouses␣of␣accommodationlong␣run␣for␣a␣short␣slidemakes␣the␣best␣of␣a␣bad␣jobMaster␣John␣Goodfellowsministries␣of␣educationmonofixation␣syndromesNorfolk␣Island␣star␣pinenot␣do␣someone␣any␣favorspersonal␣defense␣weaponpotassium␣ferrocyanidepoverty␣is␣a␣state␣of␣mindpseudologia␣fantasticaput␣one's␣affairs␣in␣orderreformulated␣gasolinesrufous-backed␣antvireosrufous-collared␣sparrowSanta␣Fe␣Island␣tortoisesends␣to␣the␣glue␣factoryset␣one's␣affairs␣in␣ordershoulder-of-mutton␣sailssoftware␣defined␣radiosstandards␣of␣comparisonstand␣on␣one's␣own␣two␣feetstand␣on␣the␣shoulders␣ofsulfur-crested␣cockatooSunday␣of␣the␣Five␣Loavestake␣someone's␣word␣for␣ittaking␣someone's␣head␣offtragedies␣of␣the␣commonstransport␣safety␣boardstwo␣sides␣of␣the␣same␣coin

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