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There are 278 twenty-one-letter words containing B, I, O and 2S

abdominohysterotomiesabdominoscrotal␣muscleabominable␣snow␣monsterabounds␣in␣one's␣own␣senseabsent-minded␣professorabsorption␣hygrometersabstract␣expressionism Abstract␣Expressionismabstract␣expressionistAlbertine␣sooty␣boubousAldabra␣giant␣tortoisesanticollaborationistsAnton-Babinski␣syndromearabinosyltransferaseArgyll␣Robertson␣pupilsAsian␣brown␣flycatchersbad␣things␣come␣in␣threesballistic␣coefficientsbanana␣equivalent␣dosesbarking␣dogs␣seldom␣bitebase␣station␣subsystemsBasset␣Artésien␣Normandbastard␣big-footed␣mousebeat␣someone's␣brains␣outBehrens-Fisher␣problemsBig␣Bend␣patchnose␣snakebinomial␣distributionsbiofunctionalisationsbisbenzylisoquinolinebiting␣someone's␣head␣offbitten␣someone's␣head␣offBjelovarsko-bilogorskablack-hooded␣antshrikesblack␣over␣Bill's␣mother'sblew␣someone's␣brains␣outblew␣this␣popsicle␣standblow␣someone's␣brains␣outblow␣this␣popsicle␣stand blow␣this␣Popsicle␣standblue-throated␣sapphiresblue-winged␣grasshopperbonfires␣of␣the␣vanitiesbootstrap␣aggregationsbreakfasts␣of␣championsbreaking␣someone's␣ballsbreaking␣someone's␣heartbrevity␣is␣the␣soul␣of␣witbring␣coals␣to␣NewcastleBroken␣Glass␣Republicanbronchoesophagoscopic broncho-esophagoscopicBrussels-Capital␣RegionBruton's␣tyrosine␣kinasebuffalobur␣nightshadesbulletin␣board␣servicesbury␣one's␣head␣in␣the␣sandbust␣a␣cap␣in␣someone's␣assbutterflies␣upon␣wheelsbutter␣someone's␣biscuitbutyrylcholinesterasecabinets␣of␣curiositiescarboxamidoadenosinescast␣pearls␣before␣swinecerebral␣localisationscerebromicroembolismscerebrovasculogenesischemosusceptibilitiesChinese␣postman␣problemchi-square␣distributionclass-based␣programmingcognitive␣disabilitiescollaborationist␣statecombat␣stress␣reactionscombination␣sandwichescombined␣braking␣systemcomfortable␣in␣one's␣skincommand␣responsibilitycommissions␣de␣bene␣essecomprador␣bourgeoisiesconfessional␣debuggingconscientious␣objectorconstituent␣assembliesconsubstantiationistscontinental␣breakfastscontrabass␣saxophonistconvertible␣securitiescounterestablishmentscounting␣one's␣blessingscyclobisintercalatorscystofilobasidiaceousdatabase␣administratorderesponsibilisationsderesponsibilizationsdesoxyribonucleosidesdesoxyribonucleotidesdielectric␣absorptionsdisembarkment␣syndromedishonorable␣dischargedisproportionablenessdistribution␣functionsDistrict␣of␣Guysboroughdo␣a␣land-office␣businessdo␣bears␣shit␣in␣the␣woodsdrives␣the␣porcelain␣busdysgammaglobulinemiasembarrassment␣of␣richesenlightened␣absolutismenterobacteriologistsesthesioneuroblastomaeverybody␣and␣his␣cousinexocellobiohydrolasesexodeoxyribonucleases

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