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There are 68 twelve-letter words containing 2D, E, M, N and Y

Adie␣syndromebloodyminded bloody-mindeddamn␣your␣hidedaydreamingsdeanonymiseddeanonymizeddecompoundlydehydroaminodemicylinderdemideifyingdemyelinateddepsidomycindermanyssidsdermanyssoiddermatodyniadeterminedlydhat␣syndromedicyanamidesdimolybdenumdipyrimidinedisembodyingdismayednessdodecylamineDown␣syndromedreamy␣DanieldummymandersDundrearyismduodenectomyduodenostomydyspigmentedendodermallyendodormancyevenmindedly even-mindedlyExon␣Domesdayfairmindedly fair-mindedlyhandmaidenlyhighmindedly high-mindedlyHOOD␣syndromehydromedusanhymenopodidshyperdiamondjudgement␣dayjudgment␣dayslymphadenoidmanyhandedly many-handedlymemory-riddenmonoaldehydemonohydratedmonohydridesopenmindedly open-mindedlyoxygen␣demandrandy␣mandiessloppy-mindedsoft-mindedlyunadmittedlyundermoneyedundismayedlyunredeemedlyweakmindedly weak-mindedlywhaddayameanwoolly-minded

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