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There are 198 sixteen-letter words containing 2D, 2I and 2S

acnidosporidiansadditive␣inversesaddressabilitiesadiadochokinesisadimensionalisedadiposis␣dolorosaAdmiralty␣Islandsanxiety␣disordersardisicrenosidesassisted␣suicidesautodisseminatedband-aid␣solutionsbipolar␣disordersbird's␣nest␣puddingbisdigitoxosidesbrickdust␣depositbridled␣titmousesCanadian␣soldierscardiodepressioncardiodepressiveChristmas␣puddingcleidomastoideusclustered␣indicesdaily␣disposablesdamsel␣in␣distressDanish␣West␣Indiesdates␣with␣destinydeconsolidationsdedensificationsdedomesticationsdefensive␣designsdeindustrialiseddeindustrialisesdeindustrializesdescription␣wordsdiamond␣crossingsDiaoyutai␣Islandsdid␣the␣impossiblediesel-hydraulicsdigalactosidasesdihydrocytosinesdiminished␣fifthsdiminished␣ninthsdiminished␣seconddiminished␣sixthsdiminished␣thirdsdiminished␣triadsdiphenoloxidasesdiplopodologistsdisappointednessdiscoglossideansdiscommendationsdiscospondylitisDiscovery␣Islandsdiscussing␣Ugandadisease␣of␣despairdisfellowshippeddishonoured␣billsdisindividualisedisintermediatesdisjointednessesdiskospondylitisdispersive␣modelsdissatisfiednessdissociative␣drugdistolasterosidedistributor␣roadsdisulfide␣bridgesdo␣as␣I␣say,␣not␣as␣I␣doDomesday␣circuitsdomestic␣disputesdry␣distillationsdsungaripteroidsdynamic␣IP␣addressedible␣bird's␣nestsendoisopeptidasefederal␣districtsfinished␣productsfloppy␣disc␣drivesfloppy␣disk␣drivesfriends␣of␣friendsgastroduodenitisgenetic␣disordersgrandstand␣finishhandicapped␣signshard␣deterministsheterodisulfideshousehold␣deitiesHudsonian␣godwitshybrid␣disgenesishydrodissectionshydrodistensionshydrodistentionshydrodistillateshydrodynamicistsidioandrosporousindividual␣sportsindustrial␣designindustry␣discountiodosuccinimidesiridescent␣cloudsiridodiagnosticslabidostommatidsLaccadive␣IslandslecanodiaspididsmeridiolestidansmicrocaddisfliesMiddle␣Easternismmidsummer␣daisiesmisdistinguishedmisunderstandingmixed␣declensionsmodified␣starchesMuddy␣Mississippimurders␣by␣suicideneohesperidosidenodulisporamidesnondisinterestedoldies␣but␣goodiesold-timer's␣disease old-timers'␣disease old␣timer's␣disease old␣timers'␣diseaseosteohydatidosispedestrian␣islandpedicellasteridsphotodissociatedplasmodiophoridspostprandial␣dipspotassium␣iodidespseudanthessiidspseudoaddictionspseudocaeciliidspseudoceratinidspseudocyclopiidspseudodiffusionspseudodimensionspseudodipeptidespseudodiscipline pseudo-disciplinepseudohaloritidspseudoidentitiespseudopalisadingpseudopimelodidspseudorapiditiespseudostigmatidspseudostratifiedpseudotirolitidsrabid␣wolf␣spidersradiodiagnosticsradiosynthesizedreindustrialisedresiduary␣devisesroadside␣thistlesSandwich␣IslanderSargodha␣Divisionsaurornithoididsschizoplasmodiidself-administered

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