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There are 114 twenty-one-letter words containing 2D, 2O and 2S

absent-minded␣professoradrenocorticosteroidsafraid␣of␣one's␣own␣shadowalkylhydroperoxidasesbarking␣dogs␣seldom␣bitebastard␣big-footed␣mousebet␣dollars␣to␣doughnutsblack-hooded␣antshrikescarboxamidoadenosineschlorodeoxyadenosinescolored␣inside␣the␣linescoming␣down␣cats␣and␣dogscoming␣down␣in␣stair␣rodsCopeland-Erdős␣constantCotswold␣morris␣dancingcould␣not␣have␣cared␣lesscrooked␣as␣a␣dog's␣hind␣legcrossed␣ladders␣problemcross␣the␣t's␣and␣dot␣the␣i'scyclodeoxynucleosidesdanced␣on␣someone's␣gravedark␣as␣the␣inside␣of␣a␣cowdarken␣someone's␣doorwaydeacetylmarsformosidedesoxyribonucleosidesdesoxyribonucleotidesdigital␣pre-distortionsdihydrosphingomyelinsdishonorable␣dischargedissociative␣disordersdo␣a␣land-office␣businessdo␣bears␣shit␣in␣the␣woodsdolichyldiphosphatasedominant␣seventh␣chordsDonaldson-Thomas␣theorydon't␣get␣someone␣starteddose␣of␣one's␣own␣medicinedot␣the␣i's␣and␣cross␣the␣t'sDr.␣Strangelove␣syndromedry␣as␣a␣dead␣dingo's␣dongaduodenoduodenostomiesDutton␣World␣SpeedwordsEddington␣luminositiesEhlers-Danlos␣syndromesendogalactosaminidaseendotransglycosidaseserrors␣of␣the␣second␣kindEurasian␣collared␣doveseverybody␣and␣his␣cousinfingers␣and␣toes␣crossedfought␣like␣cats␣and␣dogsgentiobiosylodorosideget␣one's␣ass␣handed␣to␣onegoods␣and␣services␣taxesgross␣domestic␣productshand␣someone␣their␣cardshardened␣someone's␣heartHarrod-Johnson␣diagramshave␣one's␣head␣screwed␣onHeads␣of␣the␣Valleys␣Roadhow␣do␣you␣spell␣this␣wordhydrodesulphurisationhydrogen␣gas␣electrodeshydroxyethylrutosideshydroxyprostaglandinskicked␣ass␣and␣took␣namesKöhlmeier-Degos␣diseaseleaves␣a␣lot␣to␣be␣desiredlipodepsinonapeptidesmade␣someone's␣blood␣boilMendes␣da␣Costa␣syndromemetalloendopeptidasesmonodehydroascorbatesosteochondrodysplasiaosteochondrodysplasicparacoccidiodomycosisparade␣passed␣someone␣byphosphatidylinositidephosphodehydrogenasesphysiologic␣dead␣spacesPolish␣Lowland␣Sheepdogpreferred␣stockholderspseudoachondroplasticpseudohermaphroditismpseudomonosaccharidespseudooligosaccharidepseudosclerodermatousradio␣cassette␣recorderRadish␣and␣GooseberriesRadishes␣and␣Gooseberryrose-crowned␣fruit-dovesRoss-Littlewood␣paradoxsecondary␣modern␣schoolsecond␣impact␣syndromessecond-system␣syndromesslot-loading␣disc␣drivessocial␣anxiety␣disordersoftware␣defined␣radiosstandards␣of␣comparisonstandards␣organizationstand␣on␣the␣shoulders␣ofstand␣out␣like␣dog's␣ballsstand␣up␣on␣one's␣hind␣legssternocleidomastoideistood␣out␣like␣dog's␣ballsteardrop␣tubeshoulderstool-assisted␣speedruns

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