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There are 78 twelve-letter words containing 2D, 2E, F, N and R

ad␣referendumbladder␣fernsBlind␣FreddieconfederatedDaingerfieldDangerfieldsdead␣of␣winterdeafferenteddeconfiguredDeerfieldiandefederatingdefederationdefenderlessdefendershipdefendressesdefibrinateddefibrinizeddeformednessdefragmenteddefraudmentsdeparaffineddereferencedDiffenderferdifferendumsdreadfulnessdream␣feedingdumfounderedear␣defendersend␣of␣the␣roadexpanded␣formfed␣the␣dragonfend␣and␣provefender-bender fender␣benderfenderboardsfiltered␣downforedestinedforegroundedforehandedly fore-handedlyforeordainedfreehandedly free-handedlyFriedlandersfriendliheadfriendly␣leadGarden␣of␣EdengenderfuckedgreenfoddersgutfounderedHundersfieldmiddle␣fingerMiddle␣Frenchnonfederatedoverdefendedprodefendantreconfoundedregiodefinedreidentifiedself-ordainedstrife-riddentoed␣and␣froedunbefriendedundefloweredundercraftedunderdefendsunderdefinedunderdefinesunderfeedersunderfeedingunderfleshedunderfocusedunderfundersunderproofedundershiftedunderstaffedunderstuffedword-deafness

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