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There are 109 sixteen-letter words containing 2D, 2E, M and 2S

absentmindedness absent-mindednessaccommodatednessadimensionalisedaugmented␣secondsautodisseminatedBasedow's␣syndromebloodymindedness bloody-mindednessbridled␣titmousescleidomastoideusclosedmindedness closed-mindednessdamsel␣in␣distressdead␣man's␣switchesdedomesticationsdeed␣of␣assumptiondeltoideus␣muscledependapotamusesdeskside␣computerdid␣the␣impossiblediminished␣seconddisintermediatesdispersive␣modelsdomestic␣disputesdo␣someone's␣head␣indoublemindedness double-mindednessdrives␣someone␣madendomannosidasesendorhamnosidasefeeblemindedness feeble-mindednessGardner's␣syndromegood-humourednessgood-temperednesshard␣deterministshold␣someone's␣handlower␣middle␣classmad␣hatter␣diseasemeridiolestidansmiddle-age␣spreadsMiddle␣EasternersMiddle␣Easternismmidsummer␣daisiesmidsummer␣madnessmisunderstandersmisunderstandestmisunderstandethmixed␣declensionsmodel-based␣designmodes␣of␣discoursemodified␣starchesmuddleheadednessmurders␣by␣suicidenarrowmindedness narrow-mindedness narrow␣mindednessold-timer's␣disease old-timers'␣disease old␣timer's␣disease old␣timers'␣diseaseopen-mindednessespremeditatednessprepared␣mustardspseudodimensionsPseudomacedonismpseudomagnitudespseudonormalisedpseudopimelodidspseudorandomisedpseudorandomizespseudorandomness pseudo-randomnesspseudoremaindersqueens␣of␣diamondsread␣someone's␣mindred-headed␣Eskimosrises␣from␣the␣deadSandifer␣syndromesecondary␣modernsself-administeredsemiconsolidatedsemidomesticated semi-domesticatedsemidreadnoughts semi-dreadnoughtssemistandardizedshaded-pole␣motorssimplemindedness simple-mindednesssinglemindedness single-mindednesssloppy-mindednesssmashed␣and␣dashedsmashes␣and␣dashesSneddon's␣syndromespectrum␣disorderStendhal␣syndromestrongmindedness strong-mindednesssuspended␣cymbalstendermindedness tender-mindednessuncompoundednessunderadjustmentsundocumentednessupper␣middle␣classvested␣remainders

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