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There are 40 sixteen-letter words containing 2D, E, M and 3S

absentmindedness absent-mindednessBasedow's␣syndromeclosedmindedness closed-mindednessDa␣Costa's␣syndromedamsel␣in␣distressdead␣man's␣switchesdiminished␣sixthsdispersive␣modelsdomestic␣disputesendomannosidasesmidsummer␣daisiesmidsummer␣madnessmisdistinguishedmisunderstandersmisunderstandestmodes␣of␣discourseold-timer's␣disease old-timers'␣disease old␣timer's␣disease old␣timers'␣diseaseopen-mindednessespotassium␣iodidespseudodimensionspseudorandomness pseudo-randomnesspseudostigmatidssimplemindedness simple-mindednesssinglemindedness single-mindednesssloppy-mindednesssmashed␣and␣dashedsmashes␣and␣dashesSneddon's␣syndromestrongmindedness strong-mindednesssuspended␣cymbalsswords␣of␣Damocles

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