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There are 49 sixteen-letter words containing D, E, M, O, S and 2Y

amoebic␣dysenteryamyloglycosidasebaby␣duck␣syndromeblue␣baby␣syndromeBywaters'␣syndromecelibacy␣syndromechymotrypsinatedchymotrypsinizedchytridiomycetesCockayne␣syndromecytodensitometrydacrymycetaceousdacryocystectomydesynonymizationdimethoxybenzylsdimethoxyphenylsdimethoxystyrenedimethoxystyrylsdysembryogenesisdysembryoplasticecohydrodynamicsglycosylceramidehydrosedimentaryhydrotachymetershydrothermolysishydroxyceramideshydroxydopamineshydroxymethylasehydroxyproteomeshyperthyroidismshypomannosylatedif␣I␣do␣say␣so␣myselfI'm␣twenty␣years␣oldleaky␣gut␣syndromemethylisocyanidemonoglycosylatedMoyamoya␣syndromenonmyristoylatedorders␣of␣symmetrypachydermatouslyPashayan␣syndromeperoxymolybdatespolypseudonymouspowder␣of␣sympathyradiosynovectomystylohyoid␣musclethermohydrolysisthyrohyoid␣muscleyields␣to␣maturity

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 39 words
  • Spanish Wiktionary: no word
  • Italian Wiktionary: no word
  • German Wiktionary: 6 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 2 words

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