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There are 73 twenty-one-letter words containing 2D, 2I, O and 2S

adrenocorticosteroidsafter␣all␣is␣said␣and␣doneanarcho-individualistsAsk␣a␣Stupid␣Question␣Daybarking␣dogs␣seldom␣bitecarboxamidoadenosinescardiovascular␣diseasecold␣agglutinin␣diseasecolored␣inside␣the␣linescoming␣down␣in␣stair␣rodsCotswold␣morris␣dancingdark␣as␣the␣inside␣of␣a␣cowdark␣crimson␣underwingsdatabase␣administratorDejerine-Sottas␣diseasedesacetylscillirosidedesoxyribonucleosidesdesoxyribonucleotidesdifferential␣diagnosesdifferential␣diagnosisdigital␣pre-distortionsdihydrosphingomyelinsdiscretionary␣spendingdishonorable␣dischargedisseminated␣sclerosisdissociative␣disordersdiversity␣jurisdictiondo␣a␣land-office␣businessdo␣bears␣shit␣in␣the␣woodsdolichyldiphosphatasedose␣of␣one's␣own␣medicineEddington␣luminositiesendogalactosaminidaseeverybody␣and␣his␣cousinfiddles␣while␣Rome␣burnsfield␣emission␣displaysfights␣like␣cats␣and␣dogsgentiobiosylodorosidegetting␣one's␣hands␣dirtyhydrodesulphurisationill␣doers␣are␣ill␣deemersinbreeding␣depressionsindependent␣possessiveKöhlmeier-Degos␣diseaselipodepsinonapeptidesmeadow␣grass␣dermatitisolive-sided␣flycatchersparacoccidiodomycosisparadoxical␣undressingphosphatidylinositidephysiologic␣dead␣spacespseudohermaphroditismpseudooligosaccharideRadish␣and␣Gooseberriesrained␣like␣cats␣and␣dogsReader's␣Digest␣versionsself-deserting␣avoidantsliding␣filament␣modelsslot-loading␣disc␣drivessocial␣anxiety␣disordersoftware␣defined␣radiosspotted␣whistling␣ducksstandards␣organizationstandard␣transmissionssternocleidomastoideiStudent's␣t␣distributionsuccinic␣dehydrogenasesurrender␣at␣discretionsuspends␣one's␣disbeliefTurks␣and␣Caicos␣Islandstwo-spotted␣scoliid␣waspvon␣Willebrand's␣diseaseye␣gods␣and␣little␣fishes

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