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There are 44 twenty-one-letter words containing 2D, 2L, 2O and S

adenotonsillectomizedalkylhydroperoxidasesbet␣dollars␣to␣doughnutscolored␣inside␣the␣linescould␣not␣have␣cared␣lesscrossed␣ladders␣problemcyclodeoxynucleosidesdeoxyoligonucleotidesdesoxyoligonucleotidediphosphatidylcholinedolichyldiphosphatasedonde␣esta␣la␣bibliotecadouble-barreled␣shotgunEhlers-Danlos␣syndromesendopolyploidizationsEurasian␣collared␣dovesgolden-headed␣cisticolagolden␣wonder␣killifishHeads␣of␣the␣Valleys␣Roadhemlock␣woolly␣adelgidshow␣do␣you␣spell␣this␣wordleaves␣a␣lot␣to␣be␣desiredlong-tailed␣meadowlarksloop␣disconnect␣dialingmade␣someone's␣blood␣boilmetalloendopeptidasesoligodeoxynucleotidesoligodesoxynucleotideone␣card␣shy␣of␣a␣full␣deckphosphoglyceraldehydeplayed␣up␣Old␣GooseberryPolish␣Lowland␣Sheepdogpseudoplacodiolic␣acidpulled␣someone␣down␣a␣pegring␣the␣devil's␣doorbellRoss-Littlewood␣paradoxsidereal␣orbital␣periodsilane-modified␣polymersilver-leaved␣bloodwoodslot-loading␣disc␣drivesstand␣out␣like␣dog's␣ballsstood␣out␣like␣dog's␣ballstransendomyocardiallyvoluntary␣aided␣schools

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 47 words
  • Spanish Wiktionary: 1 word
  • Italian Wiktionary: no word
  • German Wiktionary: 2 words
  • Portuguese Wiktionary: 3 words
  • Dutch Wiktionary: 12 words

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