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There are 31 twenty-one-letter words containing 2D, L, O and 3S

cardiovascular␣diseasecrossed␣ladders␣problemdesacetylscillirosidedesoxyribonucleosidesdisseminated␣sclerosisdo␣a␣land-office␣businessEhlers-Danlos␣syndromesendotransglycosidasesFalkland␣Islands␣wolvesfield␣emission␣displaysfights␣like␣cats␣and␣dogsKöhlmeier-Degos␣diseaselesser␣included␣offenseMaliseet-Passamaquoddy Maliseet–Passamaquoddyosteochondrodysplasiaosteochondrodysplasicphysiologic␣dead␣spacespseudosclerodermatousslot-loading␣disc␣drivesspotted␣whistling␣ducksstand␣on␣the␣shoulders␣ofstand␣out␣like␣dog's␣ballsstand␣up␣on␣one's␣hind␣legsstood␣out␣like␣dog's␣ballssuspends␣one's␣disbelieftool-assisted␣speedrunsTurks␣and␣Caicos␣Islandstwo-spotted␣scoliid␣waspvon␣Willebrand's␣diseaseye␣gods␣and␣little␣fishes

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