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There are 295 twenty-one-letter words containing D, 2E, 2I and 2S

abdominohysterotomiesacetylglucosaminidaseacetylhexosaminidasesadaptive␣immune␣systemsadenosinetriphosphate adenosine␣triphosphateadenotonsillectomizesadministrative␣regionsadrenocorticosteroidsafter␣all␣is␣said␣and␣doneagricultural␣densitiesanterior␣median␣fissureanticonfederationistsantitranscendentalismArndt-Eistert␣synthesisattends␣to␣one's␣knittingauctorial␣descriptivesbackwards␣time␣machinesbad␣things␣come␣in␣threesbarking␣dogs␣seldom␣bitebiting␣someone's␣head␣offblack-striped␣wallabiesblew␣this␣popsicle␣standbuilds␣castles␣in␣the␣airbulletin␣board␣servicescarboxamidoadenosinescardiovascular␣diseasecdesign␣proponentsistscellooligosaccharidescertificates␣of␣depositchemoradiosensitiserschemoradiosensitivitychronic␣wasting␣diseaseCocos␣(Keeling)␣Islanderscognitive␣disabilitiescold␣agglutinin␣diseasecolored␣inside␣the␣linescolors␣outside␣the␣linescolour␣outside␣the␣linescolours␣inside␣the␣linescombined␣braking␣systemcommissions␣de␣bene␣essecomprador␣bourgeoisiescondensation␣reactionscondensing␣locomotivesconfessional␣debuggingconstructive␣dischargecontradictionlessnesscontradistinctivenesscrystal␣radio␣receiverscuriouser␣and␣curiousercurse␣of␣dimensionalitydark␣as␣the␣inside␣of␣a␣cowdata␣processing␣machinedecompression␣sicknessdeconfessionalisationdeconfessionalizationdefect␣of␣one's␣qualitiesDejerine-Sottas␣diseasedemand␣characteristicsdemonstrative␣legaciesdenotational␣semanticsdeprofessionalizationderesponsibilisationsderesponsibilizationsderivative␣instrumentsdesacetylscillirosidedescriptive␣adjectivesdescriptive␣geometriesdescriptive␣statisticsdesoxyribonucleosidesdesoxyribonucleotidesdestructive␣criticismsdevil␣lies␣in␣the␣detailsdick-measuring␣contestsdielectric␣absorptionsdifferential␣diagnosesdifferential␣diagnosisdigital␣subscriber␣linedimensionless␣quantitydimethylpolysiloxanesdips␣one's␣toe␣in␣the␣waterdisappearing␣carriagesdiscretionary␣spendingdisestablishmentariandishonorable␣dischargedisproportionablenessdisseminated␣sclerosisdissociative␣disordersdistributed␣hash␣tablesdiversity␣is␣perversitydivisibility␣sequencesdo␣a␣land-office␣businessdo␣bears␣shit␣in␣the␣woodsdose␣of␣one's␣own␣medicinedrive␣one's␣pigs␣to␣marketdrives␣the␣porcelain␣busdyskeratosis␣congenitaEast␣Riding␣of␣YorkshireEddington␣luminositiesendogalactosaminidaseenlightened␣absolutismErdheim-Chester␣diseaseevaluative␣diversitieseverybody␣and␣his␣cousinexclusive␣disjunctionsfiddles␣while␣Rome␣burnsfield␣emission␣displaysfine-needle␣aspirationsFinnish␣forest␣reindeerfirm␣hands␣at␣the␣tillersfirm␣hands␣on␣the␣tillersflexible␣sigmoidoscopy

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