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There are 58 twenty-one-letter words containing D, E, F, I, 2S and U

anterior␣median␣fissurebastard␣big-footed␣mousebuffalobur␣nightshadesbuff-breasted␣sandpiperchondroitinsulfatasesconfessional␣debuggingcourt␣of␣second␣instancecurse␣of␣dimensionalitycystofilobasidiaceousdefect␣of␣one's␣qualitiesdesulfoglucosinolatesdo␣a␣land-office␣businessdrunk␣as␣a␣fiddler's␣bitchduress␣of␣circumstancesFallen␣Jerusalem␣Islandfiddles␣while␣Rome␣burnsfought␣like␣cats␣and␣dogsFrench␣and␣Iroquois␣WarsFrobenius␣endomorphismfructoligosaccharideshouses␣of␣accommodationif␣these␣walls␣could␣talkIslamic␣fundamentalismjump␣before␣one␣is␣pushedKyasanur␣forest␣diseaselesser␣included␣offencelesser␣included␣offenselong␣run␣for␣a␣short␣slidemagnetic␣flux␣densitiesministries␣of␣educationmoustached␣kingfisherspenny␣wise,␣pound␣foolishpostperfusion␣syndromepotassium␣ferrocyanidepressure␣gradient␣forcepseudologia␣fantasticaput␣one's␣affairs␣in␣orderreformulated␣gasolinesrequests␣for␣productionrose-crowned␣fruit-dovesrufous-backed␣antvireosrufous-capped␣antshrikerufous-winged␣antshrikeshoulder-of-mutton␣sailssingle-valued␣functionsSkeffington's␣daughterssugarcane␣soldier␣fliesSunday␣of␣the␣Five␣Loavessurface-supplied␣divingsuspends␣one's␣disbeliefsuspension␣of␣disbeliefSydney␣funnel-web␣spidertransfinite␣inductionstwenty-five-thousandersUnited␣States␣of␣Americaunsaturated␣fatty␣acidsunstraightforwardnessyouthful␣indiscretions

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