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There are 948 eighteen-letter words containing E, O, P, S and Y

(page 5)

physiopathogenesisphytophysiognomiespiezopsychrophilicpin␣a␣rose␣on␣your␣nosepiperonylonitrilespiriformis␣syndromepiss␣money␣up␣the␣wallplastohydroquinoneplay␣one's␣cards␣rightplays␣Old␣Gooseberryplays␣one's␣cards␣wellplays␣one's␣hand␣rightplay␣well␣with␣othersplay␣with␣edged␣toolsplay␣with␣house␣moneyplethysmographicalpoke␣someone's␣eye␣outPoland␣Is␣Not␣Yet␣Lostpolicy␣interest␣ratepolyacrylonitrilespolybenzimidazolespolychemotherapiespolychromatophilespolydispersibilitypolydispersivitiespolyesterificationpolyesterurethanespolyethersulphonespolyethyleneiminespolyfunctionalisedpolygalacturonasespolygalacturonatespolygamomonoeciouspolyhydroxyphenolspolymerizabilitiespolymerogenicitiespolymolecularitiespolymorphonuclearsPolynesian␣Trianglepolypharmacologiespolyphenoloxidasespolyphenylalanines poly-phenylalaninespolyphosphorylatedpolyplethysmographpolypseudorotaxanepolysporangiophytepolyunsaturated␣fatpolyvalerolactonespolyvinylchlorides polyvinyl␣chloridespolyvinylsiloxanespops␣someone's␣cherrypopular␣etymologiesportal␣hypertensionpositive␣neutralitypostconceptionallypostdepositionallypostpancreatectomypostpericardiotomypostpolymerizationpotassium␣guanylatepotassium␣hydroxidepotentiostaticallypour␣honey␣in␣one's␣earprecompositionallyprecrystallizationpredispositionallypreparatory␣subjectprephosphorylatingprephosphorylationPresidency␣divisionpresuppositionallypresymptomaticallypresynchronizationpretty␣horsebreakerprimary␣legislationprobability␣densityprobability␣measureproofs␣by␣exhaustionpropionylpromasineproposition␣playersproprietary␣eponymspropriosensitivityprosecution␣historyproselyte␣of␣the␣gateprosperity␣doctrineprosperity␣theologyproteoaminoglycansproteopolymersomesprotocycloceratidsprotodesilylationsprotoplanetary␣discprotoplanetary␣diskprototype␣extensionproximoposteriorlyprune␣belly␣syndromepseudoanaphylacticpseudobiologicallypseudocompensatorypseudoetymologicalpseudogynecomastiapseudoheritabilitypseudoheterozygouspseudohyperkalemiapseudohypertensionpseudohypertrophicpseudohyponatremiapseudoleukocytosispseudomerohedrallypseudometallophytepseudometaphysicalpseudomythologicalpseudoparaphylliumpseudophylactocarppseudopolycythemiapseudopsychologiespseudopsychopathicpseudosynaesthesiapseudouridylationspseudoxyrhophiinespseudozygopleuridspsychodermatologicpsychogalvanometerpsychogalvanometrypsychogeographicalpsychogeriatricianpsychomanipulativepsychoneurologicalpsychoneurologistspsychoneuroticallypsychopathologizedpsychopathologizespsychopharmaceuticpsychophilosophiespsychophoneticallypsychosemanticallypsychosemioticallypsychotechnologiespsychotherapeuticspsychotherapeutistpsychrometric␣chartpsychrosensitivitypulmonary␣embolismspulmonary␣emphysemapunch␣drunk␣syndrome

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 953 words
  • Spanish Wiktionary: 3 words
  • Italian Wiktionary: no word
  • German Wiktionary: 87 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 56 words

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