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There are 580 twenty-one-letter words containing 2E, M and 2S

(page 6)

trimethyltransferasesTwelve␣Days␣of␣Christmastwisting␣someone's␣wordstwo␣sides␣of␣the␣same␣cointying␣oneself␣to␣the␣masttyrannies␣of␣majoritiesUnited␣States␣of␣Americaunmasked␣one's␣batteriesupsetting␣thermometersureteroureterostomiesuse-mention␣distinctionVirchow-Seckel␣syndromevirgin␣fields␣epidemicsvisceral␣leishmaniasesvisceral␣leishmaniasisviscosupplementationswalked␣in␣someone's␣shoeswalking␣corpse␣syndromewestern␣spruce␣budwormswet␣t-shirt␣competitionswhat␣was␣someone␣smokingwhistling␣face␣syndromewho␣died␣and␣made␣you␣bossWidmanstätten␣patternswinter␣vomiting␣diseasewrapped␣one's␣arms␣aroundwritten␣in␣someone's␣faceyou␣must␣be␣fun␣at␣partiesyou␣win␣some,␣you␣lose␣some

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