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There are 330 twenty-one-letter words containing E, F, I and 2S

absent-minded␣professoradmiral␣of␣the␣Swiss␣Navyaffine␣transformationsafraid␣of␣one's␣own␣shadowafter␣all␣is␣said␣and␣doneairbreathing␣catfishesalcohol␣flush␣reactionsall␣that␣one's␣life's␣worthalternative␣lifestylesAmerican␣cliff␣swallowsaminoacyltransferasesanterior␣median␣fissureanticonfederationistsarabinosyltransferasearguments␣from␣illusionarse␣like␣a␣Japanese␣flagarteriovenous␣fistulasarticles␣of␣associationAsian␣brown␣flycatchersas␣if␣there␣is␣no␣tomorrowaustausch␣coefficientsballistic␣coefficientsbastard␣big-footed␣mouseBehrens-Fisher␣problemsbiting␣someone's␣head␣offbitten␣someone's␣head␣offbonfires␣of␣the␣vanitiesbreakfasts␣of␣championsbrevity␣is␣the␣soul␣of␣witbuckminsterfullerenesbuffalobur␣nightshadesbuff-breasted␣sandpiperbutterflies␣upon␣wheelscabinets␣of␣curiositiesCalifornia-style␣pizzascast␣one's␣net␣far␣and␣widecast␣pearls␣before␣swinecasualty␣of␣superioritycatching␣someone's␣fancycertificates␣of␣depositChinese␣fighting␣stickschondroitinsulfatasesclassification␣schemesclassification␣societyclinging␣to␣the␣skirts␣ofcome␣up␣smelling␣of␣rosescomfortable␣in␣one's␣skincompliments␣of␣the␣houseconfessional␣debuggingconfiguration␣sectionsconspiracies␣of␣silencecontinental␣breakfastscourt␣of␣second␣instancecourts␣of␣first␣instancecritical␣success␣factorcurse␣of␣dimensionalitycystofilobasidiaceouscytidylyltransferasesdances␣of␣the␣seven␣veils Dances␣of␣the␣Seven␣Veilsdark␣as␣the␣inside␣of␣a␣cowdeacetylmarsformosidedeconfessionalisationdeconfessionalizationdefect␣of␣one's␣qualitiesdeprofessionalizationdesulfoglucosinolatesdifferential␣diagnosesdifferential␣diagnosisdiphosphotransferasesdo␣a␣land-office␣businessdose␣of␣one's␣own␣medicinedrunk␣as␣a␣fiddler's␣bitchduress␣of␣circumstancesEast␣Riding␣of␣YorkshireEinstein␣refrigeratorsembarrassment␣of␣richesEmpire␣State␣of␣the␣Southequipotential␣surfaceserrors␣of␣the␣second␣kindFalkland␣Islands␣wolvesFalklands␣fritillariesFallen␣Jerusalem␣Islandfalse␣bluetail␣emo␣skinkfarm␣business␣tenanciesfasciomusculoskeletalfast␣Fourier␣transformsferroelectric␣crystalsferroelectric␣shuttersfiddles␣while␣Rome␣burnsfield␣emission␣displaysfights␣like␣cats␣and␣dogsFile␣Transfer␣Protocolsfine-needle␣aspirationsfine-structure␣constant fine␣structure␣constantfingers␣and␣toes␣crossedFinnish␣forest␣reindeerfirm␣hands␣at␣the␣tillersfirm␣hands␣on␣the␣tillersfirst␣angle␣projectionsfirst-chance␣exceptionsfirst␣cosmic␣velocitiesFirst␣New␣England␣SchoolFischer-Tropsch␣processflexible␣sigmoidoscopy

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