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There are 362 twenty-one-letter words containing E, I, M, S and Y

abdominohysterotomiesabsorption␣dynamometerabsorption␣hygrometersacetamidomethylationsacetylgalactosaminideacetylgalactosaminylsacetylglucosaminidaseacetylhexosaminidasesacetylneuraminic␣acidsadaptive␣immune␣systemsadmiral␣of␣the␣Swiss␣Navyadrenogenital␣syndromeadsorption␣calorimetryalkylaminooxadiazolesalternate␣reality␣gamesaminoacyltransferasesaminopolycarboxylatesamplitude␣spectroscopyanarcha-feministicallyAndean␣hairy␣armadillosangiotomodensitometryAnton-Babinski␣syndromearginylaminopeptidase arginyl␣aminopeptidaseasteroseismologicallyasymmetrical␣spinnakeratomic␣force␣microscopyaxiom␣of␣extensionalitybad␣money␣drives␣out␣goodbase␣station␣subsystemsbenzoylhydroxylaminesbenzyloxyphthalimidesbenzylphenethylaminesBerk-Tabatznik␣syndromebe␣still␣my␣beating␣heartblueberry␣muffin␣babiescarbamidomethylationscardioparasympatheticcardiovascular␣systemscatching␣someone's␣fancycelebrating␣Palm␣SundaychemoradiosensitivityChiari-Frommel␣syndromeChinese␣Communist␣Partychlorotrimethylsilaneclassical␣unemploymentCode␣of␣Military␣Justicecombined␣braking␣systemcomes␣with␣the␣territorycoming␣up␣with␣snake␣eyescommand␣responsibilitycommon␣squirrel␣monkeyscommunion␣ecclesiologycomputationally␣securecoordination␣chemistryCoxeter-Dynkin␣diagramsCrigler-Najjar␣syndromecrimes␣against␣humanitycurse␣of␣dimensionalitycyclomaltodextrinasescyclotetramerizationsdeacetylmarsformosidedeadly␣diamonds␣of␣deathdermatohistopathologydestroyer␣minesweepersdiabetic␣embryopathiesdialkylhydroxylaminesdicyclohexylammoniumsdidesmethyldoxylaminedihydrodesoxymorphinedihydrosphingomyelinsdiisopropylethylaminediisopropyltryptaminedimensionless␣quantitydimethoxyamphetaminesdimethoxyquinazolinesdimethylphenanthrenesdimethylphenylsilanoldimethylpolysiloxanesdisembarkment␣syndromedisjunctive␣syllogismsdocumentary␣hypothesisdomestic␣policy␣councilDunning-Kruger␣syndromedysgammaglobulinaemiadysgammaglobulinemiaseasy␣peasy␣pumpkin␣peasyelectromyostimulationelectropolymerisationemergy␣investment␣ratioemphysematous␣cystitisencephalomyelopathiesenteric␣nervous␣systemsepidemic␣polyarthritiserythrocyanosis␣crurumerythroleukemogenesisethylene␣interpolymersetymological␣argumentsEuropean␣river␣lampreyseverybody␣and␣his␣mothereveryone␣and␣his␣grandmaexploding␣head␣syndromeexploratory␣committeesexternopyramidisationfield␣emission␣displaysflexible␣sigmoidoscopyforeign␣accent␣syndromegalactopyranosylaminegalactosylceramidasesgiving␣someone␣gray␣hairgiving␣someone␣grey␣hairglint␣in␣the␣milkman's␣eyeglobotriaosylceramideGuillain-Barré␣syndromehairy-eared␣dwarf␣lemurshemilabyrinthectomieshemlock␣woolly␣adelgidshepatonephric␣syndromeheterobasidiomycetous

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 248 words
  • Spanish Wiktionary: no word
  • Italian Wiktionary: no word
  • German Wiktionary: 31 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 40 words

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