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There are 435 twenty-one-letter words containing E, P, R, T and Y

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second␣impact␣syndromesserdexmethylphenidateShipton-by-Beningbroughsialylpentasaccharideskunk␣at␣the␣garden␣partySleeping␣Beauty␣problemSocial␣Democratic␣PartysophrolaeliocattleyasSouthern␣lady's␣slippersspecific␣gravity␣bottlespectrobolometricallysphygmomanometricallyspiny␣softshell␣turtlesspondyloarthropathiesstereoencephalographystereomicroscopicallystereophotomicroscopystereospecific␣polymerstorage␣polysaccharidesuperior␣thyroid␣arterysupermultiplicativitysuperparamagneticallysupramultiplicativelysympathetic␣vibrationssyngenesiotransplantssystolic␣blood␣pressuretelevision␣personalityten␣points␣to␣Gryffindortephrochronologicallyterephthaloyl␣chloridetetrahydronaphthalenetetrahydropyrimidinestetramethylpiperidinetheoretical␣physiciststhere's␣a␣lid␣for␣every␣potthiogalactopyranosidetrain␣operating␣companytransport␣safety␣boardstrichothiodystrophiestrickle-down␣hypothesis trickle␣down␣hypothesistrifluoromethylphenyltrimethaphan␣camsylatetrimethoxyamphetaminetrimethylphenanthrenetriphenylchlorosilanetriphenylphosphoniumstrypanosusceptibilitytwo␣ha'pennies␣for␣a␣pennytypewriter␣apostrophestypographic␣apostropheunemployment␣insuranceupper␣respiratory␣tractwestern␣prickly␣juniperwhat␣is␣your␣phone␣numberwhitecoat␣hypertension white-coat␣hypertension white␣coat␣hypertensionwhite-gaped␣honeyeaterswhite-plumed␣honeyeaterxenotransplantabilityyellow-edged␣pygarctiasyou␣can't␣be␣half␣pregnantyou␣must␣be␣fun␣at␣parties

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 270 words
  • Spanish Wiktionary: 2 words
  • Italian Wiktionary: no word
  • German Wiktionary: 24 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 39 words

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