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There are 422 twelve-letter words containing E, 2I, 2M and S

academicisms Academicismsaide-memoires aide-mémoiresaides-mémoireair␣embolismsallosemitismaluminumizesambidextrismambient␣musicAmericanismsandromimesisantifeminism anti-feminismantimensiumsantisemitism anti-semitism anti-Semitismaxisymmetric axi-symmetricbetamimeticsbicameralismbimetallismsbiomagnetismbiomechanismbisymmetriesbohemianisms Bohemianismscetrimoniumschamaemyiidschemiosmosischemiosmoticchemostimulichimeriformschrombismitecimmerianismcommelinoidscommissairescommissariescommissionedcommissioneecommissionercommissivelycommitteeismcommodifierscommoditisedcommoditisescommoditizescompile␣timescosemisimplecremationismdecommissiondemipyramidsdemuslimized de-Muslimizeddemuslimizes de-Muslimizesdeterminismsdiamagnetismdiammoniatesdidemnimidesdiminishmentdimmer␣switchdisgerminomadismemberingdissymmetricecofeminismsecopessimismecumenicismsemanationismembolismaticemerimidineseminectomiesemotionalismepigrammistsepimorphismsepimysiotomyepistemicismestromimeticethnomimesiseudaimonismsfideicommissfiery␣skimmerFiji␣mermaidsformamidinesfreeswimming free-swimminggimmickeriesgimmickinessgrammaticisegrimmiaceousgymnodiminesgynemimeticshamamelididshemihedrismshemimicelleshemimorphismhemiramphidsHermesianismhermeticismsHome␣Ministerhomodimeriseimipenemasesimmaculaciesimmanentisedimmanentisesimmanentismsimmanentistsimmanentizesimmaturitiesimmediatistsimmersionismimmersionistimmersion␣oilimminentnessimmiseratingimmiserationimmiserizingimmobilisateimmobilisersimmobilitiesimmobilizersimmoderaciesimmoralitiesimmorigerousimmortalisedimmortaliserimmortalisesimmortalizesimmunevasionimmunevasiveimmunoevasinimmunokinaseimmunolesionimmunologiesimmunosilentimperialismsimperilmentsimpermissiveimpingementsimpoisonmentimprisonmentIndian␣summerintermediumsisoimmunizedisoimmunizesisomorphemicisosymmetricjamaicamidesJimmy␣RiddlesJoe␣Millerismlaminotomieslansiumamideleil␣shimurimlimbic␣systemLimerick␣hamsliving␣museumMachiavelismmacroseismicmacrosemiidsmagic␣realismmagisteriumsMaimonideansmain␣memoriesmalformitiesmammalianisemammillariesmammopoiesisManicheanismMarienbadismMaritime␣Alpsmartinetismsmasutomilitematerialismsmatrix␣mixersmaximalitiesMcEllistrimsmediaevalismmedievalismsmegamerinidsmegamillionsmegaministrymegavitaminsMeisenheimermemorialisedmemorialisermemorialisesmemorialistsmemorializesmemorisationMendelianismmenisperminemercantilismmercurialismmeristematicmeristemoidsmermaid␣skirtmesoclimaticmesokinetismmesolimnionsmesometritismesosigmoidsMessalianismmetabasidiummetakinetismmetalimnionsmetamictizesmetasemioticmetaviriomesmetaviromicsmethsuximidemicrochemistmicrocinemasmicrodentismmicrodesmidsmicrofilmersmicromeristsmicromilieusmicropygmiesmicroremainsmicroseismicmicrosiemensmicrosommitemicroswimmermicrotomizesMid-Americans

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