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There are 462 fifteen-letter words containing E, I, M, 2S and Y

activity␣streamsadenomyomatosisaerodynamicistsaeschynomenoidsagroecosystemicamidohydrolasesaminoglycosidesaminohydrolasesamyloidogenesisamylopectinosisancylostomiasesanesthesiometryangiomyogenesisankylostomiasesantihaemolysinsantimetaphysics anti-metaphysicsantiproselytismantisymmetrisedantisymmetriserantisymmetrizesarhythmogenesisarrythmogenesisasterseismologyastroseismicityastroseismologyasymmetricitiesatrioseptostomyaxiomatic␣systemaxisymmetrisingBálint's␣syndromebasidiomycetousbathylasmatinesBertillon␣systembibliomysteriesbiosystematistsbody␣mass␣indicesbutylmagnesiumscaymanostellidschemical␣physicschemical␣symbolschemolitholysischemosystematicchimney␣swallowschimneysweeperscholestyramineschrysanthemoidscleistogamouslycolymbosaurinescommunity␣chestscommunity␣nursescompassionatelycomplex␣analysiscomplexity␣classcompressibilityconsumer␣societycosmetic␣surgeryCronquist␣systemcryomicroscopescryptomedusoidscyanomyovirusescybercolumnistscyberpessimistscybersymposiumscyclodeaminasescycloisomerasescyclostrematidscypselosomatidscytochemistriesdensity␣matricesdepalmitoylasesdermathopytosisdermatomyositisdermatophytosisdesmatochelyidsDes␣Moines␣Countydichotomous␣keysdigestive␣systemdimensionlesslydimycocerosatesdisassembly␣linedisiamylboranesdisseminabilitydoomsday␣devices Doomsday␣Devicesdrainage␣systemsdynamical␣systemdynamic␣pressuredysembryoplasiadyshomoeostasisdysmorphologiesdysmyelinationsdysmyelopoiesisdysproteinemiasecosystematistseigensymmetriesemergency␣stairsendocrine␣systemEngelmann's␣daisyenterosymbiontsexpository␣lumpsextrasystematicfamily␣historiesferrisymplesitefideicommissaryfiftysomethings fifty-somethingsfirst-time␣buyersfortysomethings forty-somethingsFritsch␣syndromefusiform␣gyrusesgaming␣the␣systemgastroileostomygay␣as␣springtimegemykibivirusesgeomythologistsglycosaminidaseGorlin's␣syndromegray␣commissuresGrisel's␣syndromeHAIR-AN␣syndromesHarvey␣Smith␣signHaversian␣systemhelioseismologyHelly␣dimensionshemiascomyceteshemiglossectomyhemigossypolonehemihypesthesiahemisynchronoushemodynamicistshemosensitivityheterobasionymsHimalayan␣shrewsHis␣Royal␣Majestyhoary␣fringe␣mosshomocysteinaseshorned␣syllogismhumanly␣possibleHumphreys␣serieshydroisomerizeshydromagnesiteshydromuscoviteshylaeochampsidshymenolepidosishyperabsolutismhypercementosishyperchromasiashypercriticismshyperemphasizeshyperenthusiasmhyperhaemolysishyperinsulinismhyperlipasemiashypermastigoteshypermodernistshyperparasitismhyperpermissivehyperpotassemiahypersemigroupshypersensualismhyperstimulateshyperthrombosishypodermoclysishypoestrogenismhypogenitalismshypomagnesemiashypopotassaemiahypovitaminoseshysterectomisedhysterectomiseshysterectomizeshysteresis␣motorileovesicostomyiminohydrolasesimmunoanalysers

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