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There are 489 sixteen-letter words containing 2E, 2I, S and Y

(page 3)

physical␣comediesphysical␣sciencesphysique␣magazinephytonematicidespiezoelasticallypiezoresistivityplatypterygiinespolyamine␣oxidasepolycentricitiespolydepsipeptidepolydispersitiespolyisobutadienepolyreactivitiespredestinativelyPresbyterianizedPresbyterianizesPresleyterianismprimary␣electionsprimary␣residenceprymnesiovirusespseudodeficiencypseudoelasticitypseudopericyclicpsychedelicizingpsychic␣surgeriespsychogeneticistpsychrosensitivepyelolithotomiespyelonephritidespyrimidinedionesquality␣of␣servicequintessentiallyradial␣symmetriesradiosynthesizedradiosynthesizerraising␣an␣eyebrowrecovery␣positionredispersabilityredispersibilityregioselectivelyregioselectivityregiospecificityregioversatilityreminiscentiallyrepolymerisationreprehensibilityrepresentabilityrepresentativityreprocessabilityresidentiaryshipresiduary␣devisesrhymes-with-richesribodeoxyvirusessanitary␣engineersecurity-by-design security␣by␣designsecurity␣depositssecurity␣distancesecurity␣interestsecurity␣officerssecurity␣printerssecurity␣servicessedimentary␣basinseismogenic␣layerselenocyanic␣acidself-sufficientlysemiaccidentallysemicrystallizedsemidecidability semi-decidabilitysemihyperoceanicsemilegitimatelysemileptonicallysemipermeabilitysemipersistentlysemiprecocialitysemiproductivelysemiseparabilitysemisynchronizedsemisynthesizingserendipity␣berryserial␣polygamiesseroepidemiologyseroprotectivitysexuality␣studiessingle␣yellow␣linesixteenpenny␣nail sixteen-penny␣nail sixteen␣penny␣nailSociety␣Islanderssociocyberneticssociogeneticallyspacetime␣physicsspecies␣dysphoriasphingomyelinasespin-density␣wavesstatic␣efficiencystationary␣enginestereotypicalitysuberoxylanilidesuccinylpeptidessummary␣diligencesuperdiffusivelysuperextensivitysuperoinferiorlysuperproficiencysuperreflexivitysupersensibilitysupersensitivelysupersensitivitysymmetricalitiessynsedimentarilyteddy␣bears'␣picnicteleiochrysalidstelepsychiatristtendency␣writingstensiometricallythe␣rest␣is␣historythermoelasticitythe␣sky␣is␣the␣limitthyroidectomisedthyroidectomisesthyroidectomizestransesterifyingtriglyceridemiastrimethoxysilanetripartite␣systemtriphenylstibinetrisectionectomytwisted␣cylindersultrasensitivelyundersensitivityunderspecificityunenterprisinglyunforeseeabilityuniversity␣of␣lifeunpresentabilityunrespectabilityunsentimentalityunserviceabilityvaccine␣hesitancyvasopermeabilityvirginity␣pledgesvoice␣synthesizerwe␣live␣in␣a␣societywestern␣poison␣ivyWhiskey␣Rebellionwhite-eyed␣attilaswilhelmramsayiteWinneshiek␣CountyWinnipeg␣goldeyeswireless␣fidelityxenobiochemistryyellow␣pond-lilies yellow␣pond␣liliesYorkshire␣Terrier

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