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There are 107 sixteen-letter words containing E, 2F, I and 2S

Aesculapian␣staffaffectionatenessantisuffragettesbioeffectivenessbreakfast␣muffinsBrussels␣griffonschargés␣d'affairesChinese␣handcuffscircles␣of␣friendscones␣of␣confusioncriminal␣offensesdifferent␣storiesdifferent␣strokesdiffusiophoresisdiminished␣fifthsdisafforestationdisafforestmentsdouble-shufflingseffranchisementsfair␣suck␣of␣the␣savfalsifiabilitiesfear␣of␣missing␣outFeast␣of␣Tsing␣Mingfeels␣like␣oneselfFestival␣of␣Lightsfictitious␣forcesfifty-first␣statesfirst␣and␣foremostfirst␣five-eighthsfishes␣out␣of␣waterFive␣Books␣of␣Mosesfix␣someone's␣flintflashlightfishes flashlight␣fishesfleches␣faitieres flèches␣faîtièresfluffed␣one's␣linesforesightfulnessfriends␣of␣friendsfruit␣of␣one's␣loinsfull␣dress␣uniformFutsing␣wolf␣snakeghost␣knifefishesgifts␣from␣the␣godsground␣offensivesHausdorff␣metricsif␣I␣do␣say␣so␣myselfinfrasubspecificin␣spite␣of␣oneselfinsufferablenessknowing␣one's␣stufflast␣bursts␣of␣fireleg-of-mutton␣fistslost␣in␣the␣shuffleMexican␣standoffsnonfossiliferous non-fossiliferousoffensensitivityoffensive␣tacklesoffice␣landscapesovereffusivenesspaperless␣officesPfeiffer's␣diseasepossessive␣suffixpost-office␣orders post␣office␣ordersprofessional␣foulpseudodiffusionsrabbit's-foot␣fernsreafforestationsresource␣officerssafe␣pairs␣of␣handsscaffold␣proteinsschizoaffectivessecurity␣officersseeing␣for␣oneselfself-confinementsself-effacingnessself-fulfillmentsself-raising␣flourself-rising␣floursself-satisfactionself-sufficientlyseparable␣affixessmall␣firm␣effectsspillover␣effectsspotlight␣effectsstaff␣of␣Asclepiusstiffening␣ordersstiff-tailed␣ducksstocking-stuffers stocking␣stuffersStreisand␣effectssubdifferentialssuffering␣catfishsufficientarianssuffocation␣matessuperdiffusivelysuperdiffusivitysuperscaffoldingthermodiffusionsundersheriffriesundersheriffshipunfaithfulnesseswarrant␣of␣fitnessWilson's␣filmy␣fernworks␣one's␣tail␣off

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