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There are 96 sixteen-letter words containing E, 2P, S and 2U

all-purpose␣floursbuttons␣up␣one's␣lipcapital␣surpluseschew␣up␣and␣spit␣outchuck␣up␣the␣spongecolour␣supplementcountersupportedCyprus␣turpentinefourspine␣sculpingroup␣punishmentshangs␣up␣one's␣spurshyperpseudopilusimmunosuppresantimmunosuppresionimmunosuppresiveimmunosuppressedimmunosuppressesimmunosuppressorimpulse␣purchasesmorphosculpturedmorphosculpturesmultiple-exposure multiple␣exposuremultipurposenessnecrosuppurativeneurosuppressionneurosuppressiveoverpopulousnessoverpresumptuouspachypleurosaursPapua␣New␣Guineanspaulo-post-futurespeanut-butter␣cups peanut␣butter␣cupsperpetual␣curatespick␣up␣one's␣crumbspolypseudonymousporcupine␣pufferspresumptuousnessprostitute's␣pupilpseudepigraphouspseudocopulationpseudocopulatorypseudoepipleuralpseudoepipleuronpseudoleukopeniapseudomorphouslypseudo-penannularpseudoplasmodiumpseudopopulationpseudoprofunditypseudopseudogoutpseudothelphusidpseudoviviparousPuestow␣procedurepulls␣one's␣socks␣uppulls␣up␣one's␣sockspunctuation␣spacepunitive␣populismpurpureagitosidepushing␣up␣daisiespush␣up␣the␣daisiesputs␣out␣to␣pastureput␣up␣the␣shuttersRepublic␣of␣Cyprusrounds␣of␣applauseseptum␣pellucidumshape␣up␣or␣ship␣outsubperpendicularsupercomputationsuperhaplogroupssupermacroporoussupermastergroupsuperpermutationsuperpopulationssuperprestigioussuperpromiscuitysuperpromiscuoussuperspectacularsupersulphuretedsupersuperlative super-superlativesupersuppressionsupersusceptiblesupertherapeuticsuppositiousnesssupratherapeuticsurge␣suppressorssurprised␣Pikachusurprise␣surpriseunpresumptuouslyunpropitiousnessunprosperousnessunpurposefulnessunsupportivenessupper␣ten␣thousand

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