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There are 74 sixteen-letter words containing E, R, S and 3U

aquasilvicultureauriculariaceousauricular␣musclesblue␣sausage␣fruitbulbous␣buttercupcinereous␣vulturecloudless␣sulfurscloudless␣sulphurcounterculturishcounterculturismcounterculturistcounterpuncturescute␣as␣a␣bug␣in␣a␣rugcybersubculturesductus␣arteriosusdural␣venous␣sinusequinumerousnessextracurriculumsferruginous␣ducksFoucault␣currentsfuture␣continuousGuadalupe␣fur␣sealmodulus␣of␣rupturemousquetaire␣cuffmultituberculismmulti-user␣dungeonneuromusculatureneurovasculatureoverpresumptuousoverscrupulouslypaulo-post-futurespeanut-butter␣cups peanut␣butter␣cupsPortuguese␣GuineaPortuguese␣guitarpresumptuousnesspseudomiraculouspseudotubercularputs␣out␣to␣pastureput␣up␣the␣shuttersquantum␣computersquantum␣supremacyquasiequilibriumrumbunctiousnessSchubert␣calculusSchuler␣pendulumsscrupulousnessessecurity␣culturessub-subunderleasesugar␣substitutessulfoglucuronidesulfur␣buckwheatssulfurylfluoride sulfuryl␣fluoridesulphur␣bacteriumsulphur␣butterflysuperbureaucratssupercutaneouslysuperequilibriumsuperindustrioussuperpromiscuoussupersulphuretedsurjunctive␣groupturncurtovirusesuncourageousnessunpresumptuouslyunpurposefulnessunscrupulousnessunstructurednessureterocutaneousurethrocutaneousUssurian␣bullheadvesiculopustularvirtual␣YouTubers

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