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There are 50 sixteen-letter words containing E, 4S and Y

abscission␣layersadversely␣possessanonymous␣classesasynchronousnessAujeszky's␣diseaseboundarylessnessbusiness␣analystscategorylessnessChinese␣cypressescompassionlesslycompressed␣yeastscraniosynostosescysts␣and␣deceasesdigestive␣systemsdisassembly␣linesexpressionlesslyfamily␣businessesglasses␣à␣la␣Psycheglossy␣antshrikesHaversian␣systemshouses␣of␣assembly Houses␣of␣Assemblyhypermassivenesshysteresis␣motorsidentitylessnessLadies␣Mayoressesmetempsychosistsmiliary␣abscessesmysteriousnessesosteopsathyrosisoversystematisespay␣one's␣addressespays␣one's␣respectsphotosynthesisespropertylessnesspseudonymousnessRussian␣cypressesschoolboyishnessschoolmistresslysemisuccessfullysingle␣star␣systemsir,␣this␣is␣a␣Wendy'sspondylosyndesissystematisationssystems␣languagesunmysteriousnessunprepossessedlyunsatisfyingnessvery␣low␣mass␣starsYour␣Highnessness

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 343 words
  • Spanish Wiktionary: 1 word
  • Italian Wiktionary: no word
  • German Wiktionary: 31 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 8 words

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