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There are 53 twenty-letter words containing E, H, N, S, T and X

acetylhexosaminidaseaugmented␣sixth␣chordsbaritone␣saxophonistsbisdemethoxycurcuminbox-drawing␣characterscontrabass␣saxophonesdesmethylxanthohumoldiethylthioxanthonesdihydroxytryptaminesdimethylpolysiloxane dimethyl␣polysiloxaneexeleutherostomizingexhausted␣combinationexponential␣smoothingfirst-chance␣exceptiongrandfather␣paradoxesheptamethoxyflavonesheterogeneous␣mixturehexachloroplatinateshexadeoxynucleotideshexafluoroplatinateshexamethyldisilanizehexamethyldisilazanehexamethyldisilizanehexamethyldisiloxanehexatungstotelluratehydroxymethylbilaneshydroxystaurosporinehydroxytestosteroneshydroxythioxanthonesinextinguishablenessmethoxycyclopentenesmethoxyhydroquinonesmethylcyclohexanonesmonohydroxybenzoatesnear-death␣experiencesoligodeoxythymidinesoligodesoxythymidinephosphorus␣oxynitridephysical␣examinationspoison␣at␣the␣box␣officepolydimethylsiloxaneposthumous␣executionsscimitar-horned␣oryxessilylethynyloxyarenesnake-in-the-box␣problemSouth␣American␣gray␣foxSouth␣American␣grey␣foxstuffing␣the␣ballot␣boxsuck␣up␣all␣the␣oxygen␣insulfamethoxypyrazinesulphamethoxydiazineunextinguishableness

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 74 words
  • Spanish Wiktionary: 1 word
  • Italian Wiktionary: no word
  • German Wiktionary: 32 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 4 words

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