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There are 456 twenty-one-letter words containing 4E, R and S

absolutes␣of␣enfleurageaccelerating␣universesacetylcholinesterasesagreements␣in␣principleAlexander␣horned␣spherealternate␣reality␣gamesalternating␣series␣testalternative␣hypothesesalternative␣investmentalternative␣lifestylesannual␣general␣meetingsanterior␣scalene␣muscleArchimedean␣propertiesarse␣like␣a␣Japanese␣flagarseniuretted␣hydrogenartificially␣sweetenedas␣ever␣trod␣shoe-leather as␣ever␣trod␣shoe␣leatheras␣far␣as␣the␣eye␣could␣seeat␣Her␣Majesty's␣pleasurebar-breasted␣honeyeaterBasset␣Fauve␣de␣Bretagnebatted␣for␣the␣other␣sidebeen␣one's␣own␣worst␣enemyBehrens-Fisher␣problemsbenzenedicarboxylatesblue-breasted␣fairywrenblue␣creeping␣gromwellsbread-and-butter␣lettersbreaking␣someone's␣heartbreathe␣one's␣last␣breathbrown␣envelope␣syndromebuckminsterfullerenesbus␣replacement␣servicebutterflies␣upon␣a␣wheelbutterflies␣upon␣wheelsCalifornia␣pepper␣treescast␣pearls␣before␣swinecerebrovasculogenesisChinese␣strawberry␣treeChinese␣water␣chestnutschondroskeletogenesisClaisen␣rearrangementsclosed␣feedwater␣heatercognitive␣estrangementcolored␣inside␣the␣linescompetitive␣tenderingsconservative␣extensionconservative␣treatmentconvertible␣securitiescooperative␣federalismcountercountermeasure counter-countermeasure counter-counter-measureCounter-Enlightenmentscredit␣where␣credit's␣duecysteinyl␣leukotrienesdanced␣on␣someone's␣gravedances␣on␣someone's␣gravedefensive␣indifferencedeflection␣differencesDejerine-Sottas␣diseasedemonstrative␣legaciesdermatovenereologistsdescriptive␣adjectivesdescriptive␣geometriesdestroyer␣minesweepersdimethylphenanthrenesdips␣one's␣toe␣in␣the␣waterdon't␣get␣someone␣starteddon't␣shoot␣the␣messengerdrive␣someone␣up␣the␣walldropped␣a␣dime␣on␣someonedrove␣someone␣up␣the␣wallDuke␣of␣Exeter's␣daughtereastern␣imperial␣eagleseastern␣Orphean␣warblerEast␣European␣Shepherdseats,␣breathes,␣and␣sleepsechoencephalographiesectophosphodiesteraseEdinger-Westphal␣nucleiEilenberg-MacLane␣spaceEinstein␣refrigeratorselectrical␣resistanceselectrochemical␣serieselectrochemomechanicselectrochemotherapieselectroencephalogramselectroencephaloscopeelectrohypersensitiveelectromagnetic␣fieldselectromagnetic␣pulseselectromethanogenesiselectron␣spin␣resonanceelectrophosphorescentelectroresponsivenesselectroretinographieselectroshock␣therapieselectrostatic␣energieselegant␣crested␣tinamouemergy␣investment␣ratioEmpire␣State␣of␣the␣Southencephaloneuropathiesendodeoxyribonucleaseengine␣order␣telegraphsenteric␣nervous␣systemsenvironmental␣refugeesenvironmental␣sciencesequivalence␣principlesErdheim-Chester␣diseaseerythroleukemogenesis

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