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There are 69 twenty-one-letter words containing 3E, I, S and X

acetylhexosaminidasesbenzenedicarboxylatesbox␣oneself␣into␣a␣cornerchlorodeoxyadenosinescompetitive␣exclusionsconservative␣extensioncyclodeoxynucleosidescyclohexadepsipeptidedeoxyoligonucleotidesdeoxyribonucleotidasedesoxyoligonucleotidedesoxyribonucleosidesdesoxyribonucleotidesdideoxyribonucleosidedidesmethyldoxylaminedigital␣converter␣boxesdimethoxyamphetaminesendodeoxyribonucleaseepoxyeicosapentaenoicexecutive␣ball␣clickers Executive␣Ball␣Clickersexecutive␣ego␣functionsexistential␣quantifierexocellobiohydrolasesexodeoxyribonucleasesexploding␣head␣syndromeexploratory␣committeesexplosive␣cyclogenesesexplosive␣cyclogenesisextensional␣definitionexternal␣iliac␣arteriesexternal␣oblique␣muscleextinction␣level␣eventsextracellular␣matricesextrapetiolar␣stipulesextraterritorialitiesfirst-chance␣exceptionsFrankenstein␣complexesgirlfriend␣experiencesgoods␣and␣services␣taxeshemihexakisoctahedronheterogeneous␣mixtureshexachlorofluoresceinhexafluoroisobutylenehexamethyldisilanizedhexamethylenediaminesinner␣orbital␣complexeslexical␣correspondencelocal␣exchange␣carriersmagnetic␣flux␣densitiesMaxwell␣Street␣Polishesmethylenedioxyphenylsmethyltriethoxysilaneoligodeoxynucleotidesoligodesoxynucleotidereactive␣oxygen␣speciesreverse␣hyperextensionRNA␣expression␣patternsRNA␣expression␣profilesrunning␣for␣the␣exerciseserdexmethylphenidatesimplified␣expressionssmart-reference␣proxiestakes␣it␣to␣the␣next␣levelthree␣marks␣of␣existenceturtle␣excluder␣deviceswhen␣one␣least␣expects␣itWitherspoon-excludableWizard␣of␣Oz␣experiments

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 260 words
  • Spanish Wiktionary: 1 word
  • Italian Wiktionary: no word
  • German Wiktionary: 46 words
  • Portuguese Wiktionary: 1 word
  • Dutch Wiktionary: 21 words

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