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There are 58 twenty-one-letter words containing E, O, 2S and 2Y

acetylgalactosaminylsacylglycerophosphatesadenylpyrophosphatasealkylhydroperoxidasesbutyrylcholinesterasecasualty␣of␣superiorityCharcot-Leyden␣crystalscholecystoenterostomycholecystogastrostomycholecystojejunostomycholecystolithotripsycoronary␣artery␣diseasecyclodeoxynucleosidescysteinyl␣leukotrienesdihydrosphingomyelinsdimethylpolysiloxanesdocumentary␣hypothesisduskyshoulder␣trevallydysgranulocytopoiesiseasy␣peasy␣lemon␣squeezyemphysematous␣cystitisendotransglycosylaseserythrocyanosis␣crurumerythrophagolysosomalerythrophagolysosomeseverybody␣and␣his␣cousinfarnesylpyrophosphatehydroxyethylrutosideshyperfibrinogenolysishyperhomocysteinemiashyperphosphorylationshysterosalpingographyLevy-Hollister␣syndromelysophosphoglyceridesmannosylglycoproteinsmoney␣can't␣buy␣happinessmonoglycosylceramidesmonoglycosylglycerolsmyristoyltransferasesneuropsychophysiologynominative␣type␣systemsopen␣circulatory␣systemphenylisothiocyanatesphosphatidylglycerolspolydimethylsiloxanespolysialyltransferasepostzygosynapophysealpterygomaxillary␣fossapyrophosphohydrolasessecond-system␣syndromessee␣you␣in␣the␣funny␣pagessialylglycoconjugatesspinoprezygapophysealsupraprezygapophysealsurface␣boundary␣layerstrypanosusceptibilityvinyltrialkoxysilanesyou␣win␣some,␣you␣lose␣some

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 20 words
  • Spanish Wiktionary: no word
  • Italian Wiktionary: no word
  • German Wiktionary: 3 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 1 word

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