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There are 159 eight-letter words containing E, I, M, O and 2S

aeolisms AeolismsamebosisameiosisamitosesamositesanemosisatomisesbisemousblissomebombsiesboreismschemosiscosmesisdesmoidsdesmosindimesonsdiosmosedishomesdisomiesechoismsegotismseisosomeemissionemissoryepisomeserotismsEskimoesEsquimosexotismsfire␣mossgeosminsheroismshomeosishominesshormesisimbossedimbosserimbossesimposersimposestisohumesisomeresisozymesJemisonslesboismlissomerMelesiosmemoisesmersionsMesidorsmesisolsmesonicsmesosticMessidorMessineomestinosmestisosmestizosmidsolesminoress MinoressmisbodesmisboxesmischosemisclosemiscodesmiscomesmisdoersmishegosmishopesMisionesmislovesmismovesmisnotesmisobeysmisopensmisspokemissworemisteousmistonesmisvotesmisyokesmodistesMoesiansMoisesesmoistensmoistestMoleskisMolinsesmonishesmopinessMorissetmorrises MorrisesmortisesmosesinsMoshiersmossiestmosslikemousiestmyodesismyotisesneonismsniosomesobelismsobeseismogreismsOmanisesomissiveosmeridsosmiatesossamineostomiesphimosespi␣mesonspine-mosspomskies PomskiespromisesrisksomeSamiotessemigodsseminosesemiomassemi-orbssemiosicsemiosissemiposhsemipros semi-prossemisoft semi-softsentimossesamoidsialomesSimcoxessimoniessimoniseSisemoresixsomesSmoggiessmoke-inssmokiestsmombiessociomessodomiessodomisesoilsomesolecismsomatisesomesingsomewisespesmilostompiessymbiosetrisomeswisdomesxenismos

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