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There are 65 twelve-letter words containing E, 2I, K, O and 2S

adipokinesisangiokinasesaniseikoniasbasikulosidebisalkoxidescaryokinesischemokinesiscookie-shinesdiskectomiesepiskotisterEskimo-kissedEskimo-kisses Eskimo␣kisseseskimologist Eskimologistferrokinesisgive␣some␣skinhaptokinesishomeokinesishydrokinesisindigo␣snakeskaryokinesisKefalovrissiketoacidosiskhainaosidesKieślowskianking␣of␣spiceskinosternidsKinrossshire Kinross-shirekirk-sessionskleptobiosisklinokinesisknifestoriesKoreanisticsleukoariosisleukopoiesisleukosialinslick␣one's␣lipsmacrokinesismesokinetismmicrokinesisMioduszewskineoskippingsneurokinesisnoisemakingsnose-pickingsorthokinesisParkinsonisephagokinesisphotokinesisrisk␣aversionrisk␣one's␣lifescientibooksSierputowskisintokamidesSpikeophilesstinking␣toessuicide␣knobstask-positiveTenrikyoistsThessalonikiwhiskerinoesWierzbowskisYorkshireism

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