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There are 778 twelve-letter words containing E, I, O, 2S and 2T

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tautomerisestautomerismstectoniciststeenologiststeetotaliststeleologiststeleonomiststelephoniststelescopiststelestationstelesystolictemporaliststemporisedsttendonitisestennis␣courtstenoplastiesTenrikyoiststensiometersterrestriousterrestrosintessaratomidtesselationstessellationtestatorshiptestcrossingtesticulomastestimonialstest␣portionstestudineoustestudinoidstetanolysinstetrofosminsTeutonicisesTeutonicismstextologiststheocratisestheocratiststheofasciststheomachiststheophobiststheosophiststheranosticsthermostasisThesprotiansthin␣sectionsthioesterasethiosulfatesthiosulfitesthistledownsthrift␣storestime␣depositsTim␣Hortonsestissue␣factor'tis␣the␣seasontoadstickerstoilet␣tissuetoken␣strikestolerantiststomistominestonometriststonsilitisestonsilotomestonsil␣stonestonsil␣tennistoothinessestoploftinesstopsy-turvies topsy␣turviestoracentesisTorres␣Straittorsiometerstortiousnesstortuositiest'othersidersto␣the␣tonsilstough␣tushiestouristifiestouristinesstouristscapetourist␣treestractionlesstraitoressestransectionstransertionstranssectiontranstensiontrematopsidstribosystemstriplestorestrouser␣suitstuberositiestuboplastiestumulositiestwincestuoustwists␣of␣fatetwo␣solitudesunconsistentunctuositiesurostealithsurosternitesuterotomistsvasectomistsvirtuositiesvisitor␣teamsvitreositiesvortensitiesvoting␣systemwastes␣of␣timewaste␣sortingwater␣pistolsWest␣Pointerswhistle␣noteswhistle␣postswhistlestops whistle-stopswhite␣sapoteswill␣contestswintersports winter␣sportswinter␣stormswood-thistles

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