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There are 57 twelve-letter words containing E, N, 2P, 2R and U

buprenorphincleaner-uppercuproproteinFrench␣purplegroundhopperimproper␣nounKnabstrupperknocker-upperneurosupportnonpuerperalnonsupporterpiper␣gurnardPort-au-Princepreperfusionpreponderouspreproducingpresupernovaprison␣pursespruriceptionpteropleuronpurinoceptorpurple␣heronspurple␣martinpurple␣nurplerepurposingsriver␣pumpkinrounder-upperroundtripped round-trippedround-tripperrupicaprinesseripauperinsnapper-uppersuperaspirinsuperencryptsuperoperonssuperpartnersuperpatternsuperpersonssuperproteinsuperspinarsTyrian␣purpleunderproppedunderpropperundersupportunderwrappedunperemptoryunperspiringunpreparableunpreparedlyunpropernessunpropertiedunprosperityunprosperousupper␣garmentUpper␣NorwoodUpper␣Sorbian

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