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There are 105 fifteen-letter words containing E, 2I, 3S and Y

abscission␣layerastroseismicityauthority␣issuesbiophotolysisesbiosynthesisingbiosynthesizersbiosystematistsbissextile␣yearsbody␣mass␣indicescase-sensitivity case␣sensitivitycollisionlesslycrosshybridizescryodissectionscyberdissidents cyber-dissidents cyber␣dissidentscyberpessimistscyberscientistsdigestive␣systemdimensionlesslydisassembly␣linedispassionatelydispossessivelydissynchronizesdysangiogenesisdysmyelopoiesiseconophysicistselastoviscosityfossiliferouslyglycoscientistsgoniodysgenesisgyrostabilisersgyroviscositieshinoki␣cypresseshydroscientistshypersensitisedhypersensitiseshypersensitizeshypoperistalsishyposensitisinghysterica␣passioimperial␣systemsimpossible␣storyinassessabilityinassessibilityintersessionaryisoerythrolysisleishmanolysinslysogenisationsmicrodysgenesismilitary␣pressesmilitary␣spousesmissynchronizesneurophysicistsosmosensitivityosteomyelitisespessimisticallypetrophysicistsphysicochemistsphysiosemeiosispityriasis␣roseapneumocystiasispolydispersionspolyspecialistspseudoepiphysispsychohistoriespsychosemioticspsychotomimesispyloric␣stenosisquasisymmetriesScilly␣Islanderssemiclassicallysemiconsciouslysemisyllabaries semi-syllabariessemisynthesizedsemisynthesizesshilly-shallierssilylphosphinessixtysomethings sixty-somethingsskinnymalinksessneaky␣suspicionspirochetolysissuicide␣Tuesdayssunrise␣industrysuperstitiouslysuppressibilitysustained␣yieldsSwiss␣Army␣knivessylvian␣fissures Sylvian␣fissuressymmetrisationssympathomimesissymphysiotomiessynoviocentesissynthesizationssystematicitiessystematic␣riskssystematisationTennysonianismsunassessabilityunstressabilityyeastie␣beasties

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