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There are 132 fifteen-letter words containing E, I, M and 4S

ambiguousnessesambitiousnessesassumptiousnessbiosystematistsblemishlessnessbumptiousnessesbusinessman's␣LSDchoirmistressesChristmas␣bushesChristmas␣seasonChristmassinessChristmas's␣treescis-trans␣isomerscommissioneresscompositoressescompressionlesscompression␣setscompressivenesscrossmetathesiscruel␣mistressescyberpessimistsdesmosterolosisDISC␣assessmentsdiscomposednessdyshomoeostasisecosystematistsemotionlessnessessential␣meshesfishmongeressesgossamer␣spidersgrandmistresseshousemistressesimmunostressorsimpassionednessimperiousnessesimprecisenessesimpressiblenessimpulsivenessesinamissiblenessin␣someone's␣shoesinstant␣messagesisolated␣systemskick␣someone's␣asskiss␣someone's␣asskiss␣someone's␣hemlick␣someone's␣asslimitlessnessesmachinelessnessmaliciousnessesmarasmus␣senilismassotherapistsmeaninglessnessmercilessnessesmermaid's␣tressesmetadiscussionsmicrobusinessesmiddle-classnessmischievousnessmiserablenessesmisguidednessesmissionlessnessMississippi␣kiteMissouri␣Suckersmistakelessnessmistrustfulnessmossy␣saxifragesosmohomeostasispermissiblenesspermission␣slipsphysical␣systemsphysiosemeiosispigmentlessnesspossessionalismpostcommissurespostmastershipsprimary␣stressespromiscuousnesspromiselessnessretransmissionsride␣someone's␣assrisk␣assessmentsrumbustiousnesssargassum␣fishesschistosomiasesschoolmistressyscoutmistressesscrumptiousnesssecurity␣systemssemiprofessionssemiseriousnesssemisuppressivesemisynthesizessensationalismsserum␣sicknessessession␣musicianShaksperianismsshowbusinessmanshowbusinessmensisters␣minoress Sisters␣Minoresssmall␣businessessnowy␣mespilusesSpanish␣jasminesspasmodicalnessspineless␣sadismsportsmanlinesssqueamishnessesstationmistresssubcommissariessubpostmistresssummer␣solsticessuperassembliessupersensualismsupersessionismSwedish␣massagesswings␣and␣missesSwiss␣Army␣knivessymphoniousnesssystematic␣riskssystems␣analysissystems␣sciencesThomsen's␣diseasethyminelessnesstoastmistressestransvestitismsunimpressednessunsqueamishnessvasovasostomieswagonmistresseswearisomenesseswhimsicalnesseswhoremistresses

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