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There are 32 sixteen-letter words containing 2E, F, I, 2M and S

defence␣mechanismdefense␣mechanismde␣Moivre's␣formuladermofasciectomyeconomic␣freedomsessential␣infimumfemale␣chauvinismfragmentectomiesimplementiferousJames's␣flamingoeslife␣imprisonmentlines␣of␣scrimmagelisdexamfetaminemagnesium␣sulfatemagnesium␣sulfidemake␣the␣first␣moveMannheim␣furnacesmaster␣of␣one's␣timemechanism␣of␣deathmicrofadeometersminifluorometersmodified␣bitumensmoments␣of␣inertiamoments␣of␣silenceon␣first-name␣termsrefrigerator␣momsself-improvementssemifermentationsemimanufacturessmall␣firm␣effectssmoke-filled␣roomsstatement␣of␣claim

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