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There are 320 sixteen-letter words containing 2E, 2H, I, O and S

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hyperpiezophileshypersynchronieshypersynchronizehypophysectomieshypophysectomizehypotrehalosemiahypotrehalosemichysterorrhaphieshystrichospheresJewish␣Bolshevismkeeps␣the␣lights␣onknight␣of␣the␣shireladies␣of␣the␣nightlead␣with␣one's␣chinlighthousekeeper lighthouse␣keeperlive␣over␣the␣brushloggerhead␣shrikelost␣in␣the␣shufflelow␣speed,␣high␣dragmechanical␣horsesmechanism␣of␣deathmechanochemistrymechanosynthesismechanosyntheticmechanotherapistmesothermophilesmetaphilosophersmetaphilosophiesmetathesiophobiamethoxybiphenylsmethyldesorphinemicrohemispheresmicrohemorrhagesmove␣with␣the␣timesmycorrhizospheremythogeographies mytho-geographiesneurophilosopherNiederschopfheimnorthern␣cavefishNorthern␣IrishmenNorthern␣Rhodesiaonce␣hurt,␣twice␣shyone␣of␣those␣thingson␣the␣other␣side␣ofon␣the␣shady␣side␣ofophthalmectomiespaedophilophilesperineorrhaphiesperish␣the␣thoughtphenolphthaleinsphenophosphazinephenoxaphosphinephenylthiophenesphilosopheressesphilosopher's␣gamephoenicochroitesphosphanylidenesphosphine␣sulfidephosphoadenosinephosphocaseinatephosphoceramidesphosphocreatinesphosphodefectivephosphodeficientphosphoglyceridephosphoisomerasephosphopeptidomephosphoselectivephosphosensitivephosphosideritesphosphothreoninephosphotriestersphotochemistriesphotoheliometersphotosynthesisedphotosynthesiserphotosynthesisesphotosynthesizedphotosynthesizerphotosynthesizesphototheodolitesphylogeographiesphytogeographiesphytosiderophoreplay␣to␣the␣whistlepleochroic␣haloespolished␣the␣pearlpolishes␣the␣pearlpooh-pooh␣theoriesprosthaphaeresis prosthaphæresisprosthaphaereticpseudodiphtheriapseudohemophiliapseudothelphusidrehypothecationsrhaphoneidaceansright␣of␣sepulchrerise␣from␣the␣ashessandwich␣theoriesSchleicher␣Countyschlossmacheriteschoolteacherishscrewing␣the␣poochSea␣of␣the␣Hebridessecond␣five-eighthsee␣the␣light␣of␣dayshake␣in␣one's␣shoesshareholdershipsships␣of␣the␣desertshortsightedness short-sightednessshot␣one␣in␣the␣sinkshots␣in␣the␣lockershoulder␣checkingshoves␣in␣the␣mouthshow␣the␣white␣flagsomething␣or␣otherSouthern␣Rhodesiasouth-southerliesspheroechinocytestakeholdershipsstereolithographstrophothevosidesulfonephthaleinSumihiro's␣theoremSwedish␣Elkhoundstake-home␣vehiclestake␣it␣to␣the␣housetechnofetishiststefillah␣shel␣roshtension␣headachestheophilosopherstheophilosophiesthe␣rest␣is␣historythermoanesthesiathermochemolysisthermohaloclinesthermohalophilesthermotherapiststhe␣thick␣plottensTvenin's␣theoremthorns␣in␣the␣fleshThorpe␣Satchvillethreshing-rollers threshing␣rollersthrew␣in␣the␣spongethroneworthinessthrow␣in␣the␣spongethrows␣in␣the␣toweltrichloroethanes

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