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There are 293 sixteen-letter words containing 2E, I, 2P and 2S

alphaherpesvirusantipreparednessapophthegmatisesappetitelessnessapportionatenessappreciativenessapprehensivenessarchiepiscopatesaspergillopepsinblepharophimosesblepharoplastiescephalosporinasecouples␣therapiescryptodepressioncurlew␣sandpipersdatives␣of␣purposedesktop␣publisherdisappointednessdisfellowshippeddisplaced␣personsendoisopeptidaseenteropeptidasesepiphyseal␣platesepiscopalianizesepistolographersesophagographiesesteropeptidasesEuropean␣skippersfibrosuppressivefinless␣porpoisesfire␣philosophersfive-spice␣powdersgrizzled␣skippersheirs␣presumptivehemihyperplasiasheptopyranosideshexakisphosphatehyperbolic␣spaceshyperdispersantshyperperistalsishyperpotassaemiahyperprogressionhyperprogressivehyperpseudopilushyperspace␣driveshyperspecialistshyperspecializeshypersuppressivehypersusceptiblehypophysectomiesimmunosuppresiveimmunosuppressedimmunosuppressesimperceptivenessImpeyan␣pheasantsimpulse␣purchasesimpulse␣responsesinapplicablenessinterpretershipsisoleptospermoneJapanese␣pumpkinsJapanese␣slippersJapanese␣spindleskleptoplastidiesleadership␣spillsleporipoxvirusesleptoceratopsidsmetaperspectivesmetaphilosophersmetaphilosophiesmisappraisementsmisapprehensiblemisapprehensionsmissed␣approachesmobile␣speed␣bumpsmultipurposenessmyelosuppressingmyelosuppressionmyelosuppressiveneurosuppressionneurosuppressivenewspaperishnessOedipus␣complexesoesophagoscopiesonline␣newspapersopposed␣cylindersoppressivenessespaid␣one's␣respectspair␣of␣spectaclespalaeosubspeciespaleopedologistspalpebral␣fissurepaperless␣officespapillomagenesisparenthesis-pointparisienne␣scoopsParker's␣spinetailpartial␣pressuresparticipatressespassenger␣pigeonsPastoral␣Epistlespavement␣princesspavement␣specialspearly␣princessespencil-sharpeners pencil␣sharpenerspeople's␣republics People's␣Republicspeppermint␣stickspeptidoliposomespersonal␣pensionsperspectivationsperspective␣glasspetroleum␣spiritsphenakistiscopes phénakistiscopesphenakistoscopes phénakistoscopesphilosopheressesphilosopher's␣gamephosphanylidenesphosphine␣sulfidephosphoadenosinephosphocaseinatephosphoceramidesphosphocreatinesphosphoisomerasephosphoselectivephosphosensitivephosphosideritesphosphotriesterspillow␣princessesPineapple␣Expresspineapplegrassesplastic␣explosiveplateletpheresispocket␣symphoniespoison-pen␣letters poison␣pen␣lettersPoisson␣processespolishes␣the␣pearlpolydispersitiespoor-spiritednessporcupine␣grassespostarsphenaminepostdisplacementpostencephalitispostparacentesispostpresentationpostpresidenciespostpresidentialpre-alpha␣versionspreapprehensionsprehilbert␣spaces pre-Hilbert␣spacesprehypertensivespreimpressionistpreplanetesimalspreprocathepsinspreprofessionalspreputioplastiesprescriptionlessprescriptivenesspreserved␣in␣aspic

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