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There are 42 sixteen-letter words containing 2E, 2N, 2S and X

all␣sixes␣and␣ninesantisphexishnessat␣sixes␣and␣sevensChinese␣boxthornscomplex␣sentencescontext-sensitivedemarc␣extensionsexchange␣studentsexoconsciousnessexoconsistenciesexperimentalnessextensionalitiesexternalisationsfix␣someone's␣flintfix␣someone's␣wagonFontenay-aux-Rosesfoxes␣in␣henhousesGalois␣extensionsgender␣expressiongets␣one's␣shine␣boxgreen␣lynx␣spidersimmunoexpressingimmunoexpressioninexplicablenessinexpressivenessinexpugnablenessinextirpablenessinextricablenessin-line␣expansionsmixed␣declensionsnonexpansivenessnonheterosexuals non-heterosexualsreflux␣condensersself-examinationssingle-lens␣reflexsnuff␣box␣sea␣beansTexas␣blind␣snakestiller␣extensionsunderexpressionsunexpressivenessxanthine␣oxidases

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 182 words
  • Spanish Wiktionary: 2 words
  • Italian Wiktionary: no word
  • German Wiktionary: 34 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 4 words

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